Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase

Yazar: Corona, Angela, Masaoka, Takashi, Tocco, Graziella, Tramontano, Enzo, Le Grice, Stuart FJ
Yayımlandı Future Med Chem (2013)

A cell-free enzymatic activity assay for the evaluation of HIV-1 drug resistance to protease inhibitors

Yazar: Matsunaga, Satoko, Masaoka, Takashi, Sawasaki, Tatsuya, Morishita, Ryo, Iwatani, Yasumasa, Tatsumi, Masashi, Endo, Yaeta, Yamamoto, Naoki, Sugiura, Wataru, Ryo, Akihide
Yayımlandı Front Microbiol (2015)

Traceless Solid-Phase α-Hydroxytropolone Synthesis

Yazar: D’Erasmo, Michael P., Masaoka, Takashi, Wilson, Jennifer A., Hunte, Errol M., Beutler, John A., Le Grice, Stuart F. J., Murelli, Ryan P.
Yayımlandı Medchemcomm (2016)

Exploiting Drug-Resistant Enzymes as Tools to Identify Thienopyrimidinone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

Yazar: Masaoka, Takashi, Chung, Suhman, Caboni, Pierluigi, Rausch, Jason W., Wilson, Jennifer A., Taskent-Sezgin, Humeyra, Beutler, John A., Tocco, Graziella, Le Grice, Stuart F. J.
Baskı/Yayın Bilgisi 2013

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

Yazar: Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Masaoka, Takashi, Maccioni, Elias, Menéndez-Arias, Luis, Alcaro, Stefano, Le Grice, Stuart F. J., Tramontano, Enzo
Yayımlandı PLoS One (2016)

Sesquiterpenoid Tropolone Glycosides from Liriosma ovata

Yazar: Ma, Jun, Pawar, Rahul S., Grundel, Erich, Mazzola, Eugene P., Ridge, Clark D., Masaoka, Takashi, Le Grice, Stuart F. J., Wilson, Jennifer, Beutler, John A., Krynitsky, Alexander J.
Yayımlandı J Nat Prod (2015)

Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance

Yazar: Nakashima, Masaaki, Ode, Hirotaka, Suzuki, Koji, Fujino, Masayuki, Maejima, Masami, Kimura, Yuki, Masaoka, Takashi, Hattori, Junko, Matsuda, Masakazu, Hachiya, Atsuko, Yokomaku, Yoshiyuki, Suzuki, Atsuo, Watanabe, Nobuhisa, Sugiura, Wataru, Iwatani, Yasumasa
Yayımlandı Front Microbiol (2016)

Studies on Cycloheptathiophene-3-Carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H inhibitors

Yazar: Corona, Angela, Desantis, Jenny, Massari, Serena, Distinto, Simona, Masaoka, Takashi, Sabatini, Stefano, Esposito, Francesca, Manfroni, Giuseppe, Maccioni, Elias, Cecchetti, Violetta, Pannecouque, Christophe, Le Grice, Stuart F.J., Tramontano, Enzo, Tabarrini, Oriana
Yayımlandı ChemMedChem (2016)

Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity()

Yazar: Murelli, Ryan P., D'Erasmo, Michael P., Hirsch, Danielle R., Meck, Christine, Masaoka, Takashi, Wilson, Jennifer A., Zhang, Baofeng, Pal, Rajat K., Gallicchio, Emilio, Beutler, John A., Le Grice, Stuart F. J.
Yayımlandı Medchemcomm (2016)

Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors

Yazar: Masaoka, Takashi, Zhao, Haiyan, Hirsch, Danielle R., D'Erasmo, Michael P., Meck, Christine, Varnado, Brittany, Gupta, Ankit, Meyers, Marvin J., Baines, Joel, Beutler, John A., Murelli, Ryan P., Tang, Liang, Le Grice, Stuart F. J.
Yayımlandı Biochemistry (2016)

Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk

Yazar: Imahashi, Mayumi, Izumi, Taisuke, Watanabe, Dai, Imamura, Junji, Matsuoka, Kazuhiro, Ode, Hirotaka, Masaoka, Takashi, Sato, Kei, Kaneko, Noriyo, Ichikawa, Seiichi, Koyanagi, Yoshio, Takaori-Kondo, Akifumi, Utsumi, Makoto, Yokomaku, Yoshiyuki, Shirasaka, Takuma, Sugiura, Wataru, Iwatani, Yasumasa, Naoe, Tomoki
Baskı/Yayın Bilgisi 2014

Sensitivity of the C-Terminal Nuclease Domain of Kaposi's Sarcoma-Associated Herpesvirus ORF29 to Two Classes of Active-Site Ligands

Yazar: Miller, Jennifer T., Zhao, Haiyan, Masaoka, Takashi, Varnado, Brittany, Cornejo Castro, Elena M., Marshall, Vickie A., Kouhestani, Kaivon, Lynn, Anna Y., Aron, Keith E., Xia, Anqi, Beutler, John A., Hirsch, Danielle R., Tang, Liang, Whitby, Denise, Murelli, Ryan P., Le Grice, Stuart F. J.
Yayımlandı Antimicrob Agents Chemother (2018)