Exploiting Drug-Resistant Enzymes as Tools to Identify Thienopyrimidinone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

Antzeko izenburuak

• Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
  nork: Tocco, Graziella, et al.
  Argitaratua: (2020)
• Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase
  nork: Corona, Angela, et al.
  Argitaratua: (2013)
• Synthesis, Activity and Structural Analysis of Novel α-Hydroxytropolone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H
  nork: Chung, Suhman, et al.
  Argitaratua: (2011)
• Mutagenesis of Human Immunodeficiency Virus Reverse Transcriptase p51 Subunit Defines Residues Contributing to Vinylogous Urea Inhibition of Ribonuclease H Activity
  nork: Chung, Suhman, et al.
  Argitaratua: (2012)
• Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity()
  nork: Murelli, Ryan P., et al.
  Argitaratua: (2016)