Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H

Samankaltaisia teoksia

• Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase
  Tekijä: Corona, Angela, et al.
  Julkaistu: (2013)
• Exploiting Drug-Resistant Enzymes as Tools to Identify Thienopyrimidinone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H
  Tekijä: Masaoka, Takashi, et al.
  Julkaistu: (2013)
• Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6
  Tekijä: Corona, Angela, et al.
  Julkaistu: (2016)
• Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor
  Tekijä: Corona, Angela, et al.
  Julkaistu: (2013)
• Electron-Deficient Alkynes as Powerful Tools against Root-Knot Nematode Melodogyne incognita: Nematicidal Activity and Investigation on the Mode of Action
  Tekijä: Tocco, Graziella, et al.
  Julkaistu: (2020)