A cell-free enzymatic activity assay for the evaluation of HIV-1 drug resistance to protease inhibitors

Due to their high frequency of genomic mutations, human retroviruses often develop resistance to antiretroviral drugs. The emergence of drug-resistant human immunodeficiency virus type 1 (HIV-1) is a significant obstacle to the effective long-term treatment of HIV infection. The development of a rap...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Matsunaga, Satoko, Masaoka, Takashi, Sawasaki, Tatsuya, Morishita, Ryo, Iwatani, Yasumasa, Tatsumi, Masashi, Endo, Yaeta, Yamamoto, Naoki, Sugiura, Wataru, Ryo, Akihide
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628118/
https://ncbi.nlm.nih.gov/pubmed/26583013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01220
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