Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase

af Corona, Angela, Masaoka, Takashi, Tocco, Graziella, Tramontano, Enzo, Le Grice, Stuart FJ
Udgivet i Future Med Chem (2013)

A cell-free enzymatic activity assay for the evaluation of HIV-1 drug resistance to protease inhibitors

af Matsunaga, Satoko, Masaoka, Takashi, Sawasaki, Tatsuya, Morishita, Ryo, Iwatani, Yasumasa, Tatsumi, Masashi, Endo, Yaeta, Yamamoto, Naoki, Sugiura, Wataru, Ryo, Akihide
Udgivet i Front Microbiol (2015)

Traceless Solid-Phase α-Hydroxytropolone Synthesis

af D’Erasmo, Michael P., Masaoka, Takashi, Wilson, Jennifer A., Hunte, Errol M., Beutler, John A., Le Grice, Stuart F. J., Murelli, Ryan P.
Udgivet i Medchemcomm (2016)

Exploiting Drug-Resistant Enzymes as Tools to Identify Thienopyrimidinone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

af Masaoka, Takashi, Chung, Suhman, Caboni, Pierluigi, Rausch, Jason W., Wilson, Jennifer A., Taskent-Sezgin, Humeyra, Beutler, John A., Tocco, Graziella, Le Grice, Stuart F. J.
Udgivet 2013

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

af Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Masaoka, Takashi, Maccioni, Elias, Menéndez-Arias, Luis, Alcaro, Stefano, Le Grice, Stuart F. J., Tramontano, Enzo
Udgivet i PLoS One (2016)

Sesquiterpenoid Tropolone Glycosides from Liriosma ovata

af Ma, Jun, Pawar, Rahul S., Grundel, Erich, Mazzola, Eugene P., Ridge, Clark D., Masaoka, Takashi, Le Grice, Stuart F. J., Wilson, Jennifer, Beutler, John A., Krynitsky, Alexander J.
Udgivet i J Nat Prod (2015)

Unique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance

af Nakashima, Masaaki, Ode, Hirotaka, Suzuki, Koji, Fujino, Masayuki, Maejima, Masami, Kimura, Yuki, Masaoka, Takashi, Hattori, Junko, Matsuda, Masakazu, Hachiya, Atsuko, Yokomaku, Yoshiyuki, Suzuki, Atsuo, Watanabe, Nobuhisa, Sugiura, Wataru, Iwatani, Yasumasa
Udgivet i Front Microbiol (2016)

Studies on Cycloheptathiophene-3-Carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H inhibitors

af Corona, Angela, Desantis, Jenny, Massari, Serena, Distinto, Simona, Masaoka, Takashi, Sabatini, Stefano, Esposito, Francesca, Manfroni, Giuseppe, Maccioni, Elias, Cecchetti, Violetta, Pannecouque, Christophe, Le Grice, Stuart F.J., Tramontano, Enzo, Tabarrini, Oriana
Udgivet i ChemMedChem (2016)

Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity()

af Murelli, Ryan P., D'Erasmo, Michael P., Hirsch, Danielle R., Meck, Christine, Masaoka, Takashi, Wilson, Jennifer A., Zhang, Baofeng, Pal, Rajat K., Gallicchio, Emilio, Beutler, John A., Le Grice, Stuart F. J.
Udgivet i Medchemcomm (2016)

Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors

af Masaoka, Takashi, Zhao, Haiyan, Hirsch, Danielle R., D'Erasmo, Michael P., Meck, Christine, Varnado, Brittany, Gupta, Ankit, Meyers, Marvin J., Baines, Joel, Beutler, John A., Murelli, Ryan P., Tang, Liang, Le Grice, Stuart F. J.
Udgivet i Biochemistry (2016)

Lack of Association between Intact/Deletion Polymorphisms of the APOBEC3B Gene and HIV-1 Risk

af Imahashi, Mayumi, Izumi, Taisuke, Watanabe, Dai, Imamura, Junji, Matsuoka, Kazuhiro, Ode, Hirotaka, Masaoka, Takashi, Sato, Kei, Kaneko, Noriyo, Ichikawa, Seiichi, Koyanagi, Yoshio, Takaori-Kondo, Akifumi, Utsumi, Makoto, Yokomaku, Yoshiyuki, Shirasaka, Takuma, Sugiura, Wataru, Iwatani, Yasumasa, Naoe, Tomoki
Udgivet 2014

Sensitivity of the C-Terminal Nuclease Domain of Kaposi's Sarcoma-Associated Herpesvirus ORF29 to Two Classes of Active-Site Ligands

af Miller, Jennifer T., Zhao, Haiyan, Masaoka, Takashi, Varnado, Brittany, Cornejo Castro, Elena M., Marshall, Vickie A., Kouhestani, Kaivon, Lynn, Anna Y., Aron, Keith E., Xia, Anqi, Beutler, John A., Hirsch, Danielle R., Tang, Liang, Whitby, Denise, Murelli, Ryan P., Le Grice, Stuart F. J.
Udgivet i Antimicrob Agents Chemother (2018)