Computational methods for detecting cancer hotspots

מאת Martinez-Ledesma, Emmanuel, Flores, David, Trevino, Victor
הוצא לאור ב Comput Struct Biotechnol J (2020)

Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions

מאת Treviño, Victor, Martínez-Ledesma, Emmanuel, Tamez-Peña, José
הוצא לאור ב Sci Rep (2017)

Revealing protein networks and gene-drug connectivity in cancer from direct information

מאת Jiang, Xian-Li, Martinez-Ledesma, Emmanuel, Morcos, Faruck
הוצא לאור ב Sci Rep (2017)

Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm

מאת Martinez-Ledesma, Emmanuel, Verhaak, Roeland G.W., Treviño, Victor
הוצא לאור ב Sci Rep (2015)

Integration and comparison of different genomic data for outcome prediction in cancer

מאת Gómez-Rueda, Hugo, Martínez-Ledesma, Emmanuel, Martínez-Torteya, Antonio, Palacios-Corona, Rebeca, Trevino, Victor
הוצא לאור ב BioData Min (2015)

DRES-02. FGFR1 DRIVES RESISTANCE TO PI3K INHIBITORS VIA UP-REGULATION OF AURORA A/PLK1/CDK1 AXIS IN GLIOBLASTOMA

מאת Li, Xiaolong, Zhang, Chen, Martinez-Ledesma, Emmanuel, Gao, Feng, Yung, W K Alfred, Koul, Dimpy
הוצא לאור ב Neuro Oncol (2017)

EXTH-82. HIGH NOTCH1 EXPRESSION AND WILD-TYPE P53 DEFINE SYNERGISTIC ACTIVITY BY GAMMA SECRETASE INHIBITORS AND DOXORUBICIN IN GLIOBLASTOMAS

מאת Zhang, Chen, Martinez-Ledesma, Emmanuel, Ding, Jie, Gao, Feng, Wu, Shaofang, Yung, W K Alfred, Koul, Dimpy
הוצא לאור ב Neuro Oncol (2017)

DRES-09. THERAPEUTIC TARGETING OF CLK2 AND PI3K/mTOR IN GLIOBLASTOMA STEM CELLS

מאת Park, Soon Young, Dong, Jianwen, Martinez-Ledesma, Emmanuel, Piao, Yuji, Verhaak, Roel, Balasubramaniyan, Veerakumar, de Groot, John
הוצא לאור ב Neuro Oncol (2017)

Landscape of Germline Mutations in DNA Repair Genes for Breast Cancer in Latin America: Opportunities for PARP-Like Inhibitors and Immunotherapy

מאת Urbina-Jara, Laura Keren, Rojas-Martinez, Augusto, Martinez-Ledesma, Emmanuel, Aguilar, Dione, Villarreal-Garza, Cynthia, Ortiz-Lopez, Rocio
הוצא לאור ב Genes (Basel) (2019)

Multigene signature for predicting prognosis of patients with 1p19q co-deletion diffuse glioma

מאת Hu, Xin, Martinez-Ledesma, Emmanuel, Zheng, Siyuan, Kim, Hoon, Barthel, Floris, Jiang, Tao, Hess, Kenneth R., Verhaak, Roel G.W.
הוצא לאור ב Neuro Oncol (2017)

STEM-09. INTRINSIC INTERFERON SIGNALING REGULATES THE CELL DEATH OF GLIOBLASTOMA STEM CELLS

מאת Khan Khan, Sabbi, Martinez-Ledesma, Emmanuel, Mittal, Sandeep, Gandy, Kaitlin, Alfaro-Munoz, Kristin, Majd, Nazanin, Balasubramaniyan, Veerakumar, de Groot, John
הוצא לאור ב Neuro Oncol (2020)

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

מאת Aguirre-Gamboa, Raul, Gomez-Rueda, Hugo, Martínez-Ledesma, Emmanuel, Martínez-Torteya, Antonio, Chacolla-Huaringa, Rafael, Rodriguez-Barrientos, Alberto, Tamez-Peña, José G., Treviño, Victor
יצא לאור 2013

Wild-type TP53 defined gamma-secretase inhibitor sensitivity and synergistic activity with doxorubicin in GSCs

מאת Zhang, Chen, Martinez-Ledesma, Emmanuel, Gao, Feng, Zhang, Wei, Ding, Jie, Wu, Shaofang, Li, Xiaolong, Wu, Jimin, Yuan, Ying, Koul, Dimpy, Alfred Yung, WK
הוצא לאור ב Am J Cancer Res (2019)

BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening

מאת Ding, Jie, Wu, Shaofang, Zhang, Chen, Garyali, Arnav, Martinez-Ledesma, Emmanuel, Gao, Feng, Pokkulandra, Adarsha, Li, Xiaolong, Bristow, Christopher, Carugo, Alessandro, Koul, Dimpy, Yung, WK Alfred
הוצא לאור ב Am J Cancer Res (2019)

TumorFusions: an integrative resource for cancer-associated transcript fusions

מאת Hu, Xin, Wang, Qianghu, Tang, Ming, Barthel, Floris, Amin, Samirkumar, Yoshihara, Kosuke, Lang, Frederick M, Martinez-Ledesma, Emmanuel, Lee, Soo Hyun, Zheng, Siyuan, Verhaak, Roel G W
הוצא לאור ב Nucleic Acids Res (2018)

EXTH-12. EFFECT OF THE PROTEIN ARGININE METHYLTRANSFERASE PRMT5 INHIBITION IN GLIOMA STEM-LIKE CELLS

מאת Mittal, Sandeep, Shaw, Vikram, Piao, Yuji, Young Park, Soon, Sriram, Sai, Dong, Jianwen, Martinez-Ledesma, Emmanuel, Henry, Verlene, Ezhilarasan, Ravesanker, Sulman, Erik, Balasubramaniyan, Veerakumar, de Groot, John
הוצא לאור ב Neuro Oncol (2018)

Depletion of CLK2 sensitizes glioma stem-like cells to PI3K/mTOR and FGFR inhibitors

מאת Park, Soon Young, Mittal, Sandeep, Dong, Jianwen, Jeong, Kangjin, Martinez-Ledesma, Emmanuel, Piao, Yuji, Khan, Sabbir, Henry, Verlene, Verhaak, Roel GW, Majd, Nazanin, Balasubramaniyan, Veerakumar, de Groot, John F
הוצא לאור ב Am J Cancer Res (2020)

The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells

מאת Dong, Jianwen, Park, Soon Young, Nguyen, Nghi, Ezhilarasan, Ravesanker, Martinez-Ledesma, Emmanuel, Wu, Shaofang, Henry, Verlene, Piao, Yuji, Tiao, Ningyi, Brunell, David, Stephan, Clifford, Verhaak, Roel, Sulman, Erik, Balasubramaniyan, Veerakumar, de Groot, John F.
הוצא לאור ב Oncotarget (2018)

Systematic analysis of telomere length and somatic alterations in 31 cancer types

מאת Barthel, Floris P., Wei, Wei, Tang, Ming, Martinez-Ledesma, Emmanuel, Hu, Xin, Amin, Samirkumar B., Akdemir, Kadir C., Seth, Sahil, Song, Xingzhi, Wang, Qianghu, Lichtenberg, Tara, Hu, Jian, Zhang, Jianhua, Zheng, Siyuan, Verhaak, Roel G.W.
הוצא לאור ב Nat Genet (2017)

Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression

מאת Fiziev, Petko, Akdemir, Kadir C., Miller, John P., Keung, Emily Z., Samant, Neha S., Sharma, Sneha, Natale, Christopher A., Terranova, Christopher J., Maitituoheti, Mayinuer, Amin, Samirkumar B., Martinez-Ledesma, Emmanuel, Dhamdhere, Mayura, Axelrad, Jacob B., Shah, Amiksha, Cheng, Christine S., Mahadeshwar, Harshad, Seth, Sahil, Barton, Michelle C., Propopotov, Alexei, Tsai, Kenneth Y., Davies, Michael A., Garcia, Benjamin A., Amit, Ido, Chin, Lynda, Ernst, Jason, Rai, Kunal
הוצא לאור ב Cell Rep (2017)