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Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions

Previous methods proposed for the detection of cancer driver mutations have been based on the estimation of background mutation rate, impact on protein function, or network influence. In this paper, we instead focus on those factors influencing patient survival. To this end, an approximation of the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Treviño, Victor, Martínez-Ledesma, Emmanuel, Tamez-Peña, José
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327384/
https://ncbi.nlm.nih.gov/pubmed/28240231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43350
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