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Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions

Previous methods proposed for the detection of cancer driver mutations have been based on the estimation of background mutation rate, impact on protein function, or network influence. In this paper, we instead focus on those factors influencing patient survival. To this end, an approximation of the...

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Publicat a:Sci Rep
Autors principals: Treviño, Victor, Martínez-Ledesma, Emmanuel, Tamez-Peña, José
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327384/
https://ncbi.nlm.nih.gov/pubmed/28240231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43350
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