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A novel missense-mutation-related feature extraction scheme for ‘driver’ mutation identification

Motivation: It becomes widely accepted that human cancer is a disease involving dynamic changes in the genome and that the missense mutations constitute the bulk of human genetic variations. A multitude of computational algorithms, especially the machine learning-based ones, has consequently been pr...

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書誌詳細
主要な著者: Tan, Hua, Bao, Jiguang, Zhou, Xiaobo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496432/
https://ncbi.nlm.nih.gov/pubmed/23044540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts558
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