Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology

von Maphis, Nicole M., Jiang, Shanya, Binder, Jessica, Wright, Carrie, Gopalan, Banu, Lamb, Bruce T., Bhaskar, Kiran
Veröffentlicht in Front Mol Neurosci (2017)

Loss of tau rescues inflammation-mediated neurodegeneration

von Maphis, Nicole, Xu, Guixiang, Kokiko-Cochran, Olga N., Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T., Bhaskar, Kiran
Veröffentlicht in Front Neurosci (2015)

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

von Maphis, Nicole, Xu, Guixiang, Kokiko-Cochran, Olga N., Jiang, Shanya, Cardona, Astrid, Ransohoff, Richard M., Lamb, Bruce T., Bhaskar, Kiran
Veröffentlicht in Brain (2015)

Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology

von Maphis, Nicole, Jiang, Shanya, Xu, Guixiang, Kokiko-Cochran, Olga N., Roy, Saktimayee M., Van Eldik, Linda J., Watterson, D. Martin, Lamb, Bruce T., Bhaskar, Kiran
Veröffentlicht in Alzheimers Res Ther (2016)

Microglial Derived Tumor Necrosis Factor-α Drives Alzheimer’s Disease-Related Neuronal Cell Cycle Events

von Bhaskar, Kiran, Maphis, Nicole, Xu, Guixiang, Varvel, Nicholas H., Kokiko-Cochran, Olga N, Weick, Jason P., Staugaitis, Susan M., Cardona, Astrid, Ransohoff, Richard M., Herrup, Karl, Lamb, Bruce T.
Veröffentlicht 2013

Photoreceptor Degeneration, Azoospermia, Leukoencephalopathy, and Abnormal RPE Cell Function in Mice Expressing an Early Stop Mutation in CLCN2

von Edwards, Malia M., de Evsikova, Caralina Marín, Collin, Gayle B., Gifford, Elaine, Wu, Jiang, Hicks, Wanda L., Whiting, Carrie, Varvel, Nicholas H., Maphis, Nicole, Lamb, Bruce T., Naggert, Jürgen K., Nishina, Patsy M., Peachey, Neal S.
Veröffentlicht 2010

Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction

von Raz, Limor, Bhaskar, Kiran, Weaver, John, Marini, Sandro, Zhang, Quanguang, Thompson, Jeffery F., Espinoza, Candice, Iqbal, Sulaiman, Maphis, Nicole M., Weston, Lea, Sillerud, Laurel O., Caprihan, Arvind, Pesko, John C., Erhardt, Erik B., Rosenberg, Gary A.
Veröffentlicht in Neurobiol Dis (2018)

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential

von Chauhan, Santosh, Ahmed, Zahra, Bradfute, Steven B., Arko-Mensah, John, Mandell, Michael A., Won Choi, Seong, Kimura, Tomonori, Blanchet, Fabien, Waller, Anna, Mudd, Michal H., Jiang, Shanya, Sklar, Larry, Timmins, Graham S., Maphis, Nicole, Bhaskar, Kiran, Piguet, Vincent, Deretic, Vojo
Veröffentlicht in Nat Commun (2015)

Genetically enhancing the expression of chemokine domain of CX(3)CL1 fails to prevent tau pathology in mouse models of tauopathy

von Bemiller, Shane M., Maphis, Nicole M., Formica, Shane V., Wilson, Gina N., Miller, Crystal M., Xu, Guixiang, Kokiko-Cochran, Olga N., Kim, Ki-Wook, Jung, Steffen, Cannon, Judy L., Crish, Samuel D., Cardona, Astrid E., Lamb, Bruce T., Bhaskar, Kiran
Veröffentlicht in J Neuroinflammation (2018)

Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy

von Maphis, Nicole M., Peabody, Julianne, Crossey, Erin, Jiang, Shanya, Jamaleddin Ahmad, Fadi A., Alvarez, Maria, Mansoor, Soiba Khalid, Yaney, Amanda, Yang, Yirong, Sillerud, Laurel O., Wilson, Colin M., Selwyn, Reed, Brigman, Jonathan L., Cannon, Judy L., Peabody, David S., Chackerian, Bryce, Bhaskar, Kiran
Veröffentlicht in NPJ Vaccines (2019)