Antitumor RNases: killer's secrets

Por Mitkevich, Vladimir A, Ilinskaya, Olga N, Makarov, Alexander A
Publicado no Cell Cycle (2015)

Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

Por Barykin, Evgeny P., Mitkevich, Vladimir A., Kozin, Sergey A., Makarov, Alexander A.
Publicado no Front Genet (2017)

The effect of net charge on the solubility, activity, and stability of ribonuclease Sa

Por Shaw, Kevin L., Grimsley, Gerald R., Yakovlev, Gennady I., Makarov, Alexander A., Pace, C. Nick
Publicado em 2001

Cytotoxicity of RNase Sa to the acute myeloid leukemia Kasumi-1 cells depends on the net charge

Por Mitkevich, Vladimir A., Burnysheva, Ksenia M., Ilinskaya, Olga N., Pace, C. Nick, Makarov, Alexander A.
Publicado no Oncoscience (2014)

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

Por Hauryliuk, Vasili, Mitkevich, Vladimir A., Eliseeva, Natalia A., Petrushanko, Irina Yu., Ehrenberg, Måns, Makarov, Alexander A.
Publicado em 2008

Changing the net charge from negative to positive makes ribonuclease Sa cytotoxic

Por Ilinskaya, Olga N., Dreyer, Florian, Mitkevich, Vladimir A., Shaw, Kevin L., Pace, C. Nick, Makarov, Alexander A.
Publicado em 2002

Stathmin/Op18 is a novel mediator of vinblastine activity

Por Devred, Francois, Tsvetkov, Philipp O., Barbier, Pascale, Allegro, Diane, Horwitz, Susan Band, Makarov, Alexander A., Peyrot, Vincent
Publicado em 2008

Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct

Por Mitkevich, Vladimir A., Kononenko, Artem V., Petrushanko, Irina Yu., Yanvarev, Dmitry V., Makarov, Alexander A., Kisselev, Lev L.
Publicado em 2006

Contribution of active site residues to the activity and thermal stability of ribonuclease Sa

Por Yakovlev, Gennady I., Mitkevich, Vladimir A., Shaw, Kevin L., Trevino, Saul, Newsom, Stephanie, Pace, C. Nick, Makarov, Alexander A.
Publicado em 2003

Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process

Por Reshetnikov, Roman V., Sponer, Jiri, Rassokhina, Olga I., Kopylov, Alexei M., Tsvetkov, Philipp O., Makarov, Alexander A., Golovin, Andrey V.
Publicado em 2011

GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner

Por Mitkevich, Vladimir A., Shyp, Viktoriya, Petrushanko, Irina Yu., Soosaar, Aksel, Atkinson, Gemma C., Tenson, Tanel, Makarov, Alexander A., Hauryliuk, Vasili
Publicado em 2012

Folding units in calcium vector protein of amphioxus: Structural and functional properties of its amino- and carboxy-terminal halves

Por Baladi, Sibyl, Tsvetkov, Philipp O., Petrova, Tatiana V., Takagi, Takashi, Sakamoto, Hiroshi, Lobachov, Vladimir M., Makarov, Alexander A., Cox, Jos A.
Publicado em 2001

Minimal Zn(2+) Binding Site of Amyloid-β

Por Tsvetkov, Philipp O., Kulikova, Alexandra A., Golovin, Andrey V., Tkachev, Yaroslav V., Archakov, Alexander I., Kozin, Sergey A., Makarov, Alexander A.
Publicado em 2010

NMR Solution Structure of Rat Aβ(1–16): Toward Understanding the Mechanism of Rats' Resistance to Alzheimer's Disease

Por Istrate, Andrey N., Tsvetkov, Philipp O., Mantsyzov, Alexey B., Kulikova, Alexandra A., Kozin, Sergey A., Makarov, Alexander A., Polshakov, Vladimir I.
Publicado em 2012

Critical role of γ-phosphate in structural transition of Na,K-ATPase upon ATP binding

Por Petrushanko, Irina Yu., Mitkevich, Vladimir A., Anashkina, Anastasia A., Klimanova, Elizaveta A., Dergousova, Elena A., Lopina, Olga D., Makarov, Alexander A.
Publicado em 2014

Basal Glutathionylation of Na,K-ATPase α-Subunit Depends on Redox Status of Cells during the Enzyme Biosynthesis

Por Mitkevich, Vladimir A., Petrushanko, Irina Yu., Poluektov, Yuri M., Burnysheva, Ksenia M., Lakunina, Valentina A., Anashkina, Anastasia A., Makarov, Alexander A.
Publicado no Oxid Med Cell Longev (2016)

Oxidation of Са(2+)-Binding Domain of NADPH Oxidase 5 (NOX5): Toward Understanding the Mechanism of Inactivation of NOX5 by ROS

Por Petrushanko, Irina Yu, Lobachev, Vladimir M., Kononikhin, Alexey S., Makarov, Alexander A., Devred, Francois, Kovacic, Hervé, Kubatiev, Aslan A., Tsvetkov, Philipp O.
Publicado no PLoS One (2016)

Effect of Reduction of Redox Modifications of Cys-Residues in the Na,K-ATPase α1-Subunit on Its Activity

Por Dergousova, Elena A., Petrushanko, Irina Yu., Klimanova, Elizaveta A., Mitkevich, Vladimir A., Ziganshin, Rustam H., Lopina, Olga D., Makarov, Alexander A.
Publicado no Biomolecules (2017)

Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins

Por Mitkevich, Vladimir A., Burnysheva, Ksenia M., Petrushanko, Irina Yu, Adzhubei, Alexei A., Schulga, Alexey A., Chumakov, Peter M., Makarov, Alexander A.
Publicado no Oncotarget (2017)

Triple-stage mass spectrometry unravels the heterogeneity of an endogenous protein complex

Por Ben-Nissan, Gili, Belov, Mikhail E., Morgenstern, David, Levin, Yishai, Dym, Orly, Arkind, Galina, Lipson, Carni, Makarov, Alexander A., Sharon, Michal
Publicado no Anal Chem (2017)