Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins

In this study, we determined whether binase, a ribonuclease from Bacillus pumilus, increases interferon sensitivity and apoptosis in SiHa cervical cancer cells infected with high-risk human papilloma virus (HPV) strain 16. Binase treatment increased SiHa cell apoptosis in a time- and concentration-d...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mitkevich, Vladimir A., Burnysheva, Ksenia M., Petrushanko, Irina Yu, Adzhubei, Alexei A., Schulga, Alexey A., Chumakov, Peter M., Makarov, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641160/
https://ncbi.nlm.nih.gov/pubmed/29069817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20199
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