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Critical role of γ-phosphate in structural transition of Na,K-ATPase upon ATP binding
Active transport of sodium and potassium ions by Na,K-ATPase is accompanied by the enzyme conformational transition between E1 and E2 states. ATP and ADP bind to Na,K-ATPase in the E1 conformation with similar affinity but the properties of enzyme in complexes with these nucleotides are different. W...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4044624/ https://ncbi.nlm.nih.gov/pubmed/24893715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05165 |
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