CAR T Cell Therapy for Neuroblastoma

Autor Richards, Rebecca M., Sotillo, Elena, Majzner, Robbie G.
Vydáno v Front Immunol (2018)

IMMU-55. GD2 IS A MACROPHAGE CHECKPOINT MOLECULE AND COMBINED GD2/CD47 BLOCKADE RESULTS IN SYNERGISTIC EFFECTS AGAINST GD2 POSITIVE MALIGNANCIES

Autor Theruvath, Johanna, Mount, Christopher, Monje, Michelle, Mackall, Crystal, Majzner, Robbie
Vydáno v Neuro Oncol (2020)

Immune-Based Approaches for the Treatment of Pediatric Malignancies

Autor Bosse, Kristopher R., Majzner, Robbie G., Mackall, Crystal L., Maris, John M.
Vydáno v Annu Rev Cancer Biol (2020)

IMMU-09. LOCALLY ADMINISTERED CAR T CELLS DEMONSTRATE MOST FAVORABLE ROUTE OF ADMINISTRATION IN A MODEL OF ATRT

Autor Theruvath, Johanna, Graef, Claus Moritz, Heitzeneder, Sabine, Majzner, Robbie, Labanieh, Louai, Mackall, Crystal
Vydáno v Neuro Oncol (2019)

PDTM-39. GD2-DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA

Autor Mount, Christopher, Majzner, Robbie, Sundaresh, Shree, Arnold, Evan, Kadapakkam, Meena, Monje-Deisseroth, Michelle, Mackall, Crystal
Vydáno v Neuro Oncol (2017)

ATRT-25. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON ATYPICAL RHABDOID TERATOID TUMOR (ATRT) AND IS A PROMISING CANDIDATE FOR CAR T CELL THERAPY

Autor Theruvath, Johanna, Graef, Claus-Moritz, Heitzeneder, Sabine, Majzner, Robbie, Mitra, Siddhartha, Cheshier, Samuel H, Mackall, Crystal
Vydáno v Neuro Oncol (2018)

IMMU-07. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON MEDULLOBLASTOMA AND PROVES TO BE A PROMISING CANDIDATE FOR CAR T CELL IMMUNOTHERAPY

Autor Theruvath, Johanna, Heitzeneder, Sabine, Majzner, Robbie, Moritz Graef, Claus, Cui, Karen, Nellan, Anandani, H Cheshier, Samuel, Mackall, Crystal, Mitra, Siddhartha
Vydáno v Neuro Oncol (2017)

IMMU-45. CHECKPOINT MOLECULE B7-H3 IS HIGHLY EXPRESSED ON MEDULLOBLASTOMA AND PROVES TO BE A PROMISING CANDIDATE FOR CAR T CELL IMMUNOTHERAPY

Autor Theruvath, Johanna, Heitzeneder, Sabine, Majzner, Robbie, Cui, Karen, Nellan, Anandani, Graef, Claus Moritz, Cheshier, Samuel H, Mackall, Crystal, Mitra, Siddhartha S
Vydáno v Neuro Oncol (2017)

DIPG-36. ANTI-GD2 CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF HISTONE 3 K27M MUTANT DIFFUSE MIDLINE GLIOMA

Autor Mount, Christopher, Majzner, Robbie, Sundaresh, Shree, Arnold, Evan, Kadapakkam, Meena, Haile, Samuel, Labanieh, Louai, Woo, Pamelyn, Rietberg, Skyler, Vogel, Hannes, Monje, Michelle, Mackall, Crystal
Vydáno v Neuro Oncol (2018)

Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells

Autor Nellan, Anandani, Rota, Christopher, Majzner, Robbie, Lester-McCully, Cynthia M., Griesinger, Andrea M., Mulcahy Levy, Jean M., Foreman, Nicholas K., Warren, Katherine E., Lee, Daniel W.
Vydáno v J Immunother Cancer (2018)

Identification of dual positive CD19+/CD3+ T cells in a leukapheresis product undergoing CAR transduction: a case report

Autor Schultz, Liora, Patel, Shabnum, Davis, Kara Lynn, Ramakrishna, Sneha, Sahaf, Bita, Bhatia, Neehar, Baggott, Christina, Erickson, Courtney, Majzner, Robbie G, Oak, Jean, Bertaina, Alice, Mackall, Crystal, Feldman, Steven
Vydáno v J Immunother Cancer (2020)

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

Autor Walker, Alec J., Majzner, Robbie G., Zhang, Ling, Wanhainen, Kelsey, Long, Adrienne H., Nguyen, Sang M., Lopomo, Paola, Vigny, Marc, Fry, Terry J., Orentas, Rimas J., Mackall, Crystal L.
Vydáno v Mol Ther (2017)

Post-Transplant Cyclophosphamide after Bone Marrow Transplantation is not Associated with an Increased Risk of Donor Derived Malignancy

Autor Majzner, Robbie G., Mogri, Huzefa, Varadhan, Ravi, Brown, Patrick, Cooke, Kenneth R., Bolaños-Meade, Javier, Swinnen, Lode, Kanakry, Jennifer, Luznik, Leo, Jones, Rick, Fuchs, Ephraim, Ambinder, Rich, Kasamon, Yvette, Symons, Heather J.
Vydáno v Biol Blood Marrow Transplant (2017)

Potent antitumor efficacy of anti-GD2 CAR T-cells in H3K27M+ diffuse midline gliomas

Autor Mount, Christopher W., Majzner, Robbie G., Sundaresh, Shree, Arnold, Evan P., Kadapakkam, Meena, Haile, Samuel, Labanieh, Louai, Hulleman, Esther, Woo, Pamelyn J., Rietberg, Skyler P., Vogel, Hannes, Monje, Michelle, Mackall, Crystal L.
Vydáno v Nat Med (2018)

Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins

Autor Blaeschke, Franziska, Stenger, Dana, Apfelbeck, Antonia, Cadilha, Bruno L., Benmebarek, Mohamed-Reda, Mahdawi, Jasmin, Ortner, Eva, Lepenies, Mareike, Habjan, Nicola, Rataj, Felicitas, Willier, Semjon, Kaeuferle, Theresa, Majzner, Robbie G., Busch, Dirk H., Kobold, Sebastian, Feuchtinger, Tobias
Vydáno v Blood Cancer J (2021)

c-Jun overexpression in CAR T cells induces exhaustion resistance

Autor Lynn, Rachel C., Weber, Evan W., Sotillo, Elena, Gennert, David, Xu, Peng, Good, Zinaida, Anbunathan, Hima, Lattin, John, Jones, Robert, Tieu, Victor, Nagaraja, Surya, Granja, Jeffrey, DeBourcy, Charles, Majzner, Robbie, Satpathy, Ansuman T., Quake, Stephen R., Monje, Michelle, Chang, Howard, Mackall, Crystal L.
Vydáno v Nature (2019)

Immune receptor inhibition through enforced phosphatase recruitment

Autor Fernandes, Ricardo A., Su, Leon, Nishiga, Yoko, Ren, Junming, Bhuiyan, Aladdin M., Cheng, Ning, Kuo, Calvin J., Picton, Lora K., Ohtsuki, Shozo, Majzner, Robbie G., Rietberg, Skyler P., Mackall, Crystal L., Yin, Qian, Ali, Lestat R., Yang, Xinbo, Savvides, Christina S., Sage, Julien, Dougan, Michael, Garcia, K. Christopher
Vydáno v Nature (2020)

Tuning the Antigen Density Requirement for CAR T Cell Activity

Autor Majzner, Robbie G., Rietberg, Skyler P., Sotillo, Elena, Dong, Rui, Vachharajani, Vipul T., Labanieh, Louai, Myklebust, June H., Kadapakkam, Meena, Weber, Evan W., Tousley, Aidan M., Richards, Rebecca M., Heitzeneder, Sabine, Nguyen, Sang M., Wiebking, Volker, Theruvath, Johanna, Lynn, Rachel C., Xu, Peng, Dunn, Alexander R., Vale, Ronald D., Mackall, Crystal L.
Vydáno v Cancer Discov (2020)

Charting a Path for Prioritization of Novel Agents for Clinical Trials in Osteosarcoma: a Report from the Children’s Oncology Group New Agents for Osteosarcoma Task Force

Autor Whittle, Sarah B., Offer, Katharine, Roberts, Ryan D., LeBlanc, Amy, London, Cheryl, Majzner, Robbie G., Huang, Alex Y., Houghton, Peter, Cordero, E. Alejandro Sweet, Grohar, Patrick J., Isakoff, Michael, Bishop, Michael W., Stewart, Elizabeth, Slotkin, Emily K., Greengard, Emily, Borinstein, Scott C., Navid, Fariba, Gorlick, Richard, Janeway, Katherine A., Reed, Damon R., Hingorani, Pooja
Vydáno v Pediatr Blood Cancer (2021)

CD22-CAR T Cells Induce Remissions in CD19-CAR Naïve and Resistant B-ALL

Autor Fry, Terry J., Shah, Nirali N., Orentas, Rimas J., Stetler-Stevenson, Maryalice, Yuan, Constance M., Ramakrishna, Sneha, Wolters, Pamela, Martin, Staci, Delbrook, Cindy, Yates, Bonnie, Shalabi, Haneen, Fountaine, Thomas J., Shern, Jack F., Majzner, Robbie G., Stroncek, David F., Sabatino, Marianna, Feng, Yang, Dimitrov, Dimiter S., Zhang, Ling, Nguyen, Sang, Qin, Haiying, Dropulic, Boro, Lee, Daniel W., Mackall, Crystal L.
Vydáno v Nat Med (2017)