PDTM-39. GD2-DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELLS AS A POTENT IMMUNOTHERAPY REGIMEN IN XENOGRAFT MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is a universally fatal pediatric brainstem tumor with a median survival of approximately 10 months. Despite advances in understanding the molecular origins of DIPG, translations to improvement in clinical outcomes have yet to materialize. To date, there has be...

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Pubblicato in:Neuro Oncol
Autori principali: Mount, Christopher, Majzner, Robbie, Sundaresh, Shree, Arnold, Evan, Kadapakkam, Meena, Monje-Deisseroth, Michelle, Mackall, Crystal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692904/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.802
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