Galantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome

по Simoes de Souza, Fabio M., Busquet, Nicolas, Blatner, Megan, Maclean, Kenneth N., Restrepo, Diego
Опубликовано 2011

Altered hepatic sulfur metabolism in cystathionine β-synthase-deficient homocystinuria: regulatory role of taurine on competing cysteine oxidation pathways

по Jiang, Hua, Stabler, Sally P., Allen, Robert H., Abman, Steven H., Maclean, Kenneth N.
Опубликовано в: FASEB J (2014)

Effects of Neonatal Neural Progenitor Cell Implantation on Adult Neuroanatomy and Cognition in the Ts65Dn Model of Down Syndrome

по Rachubinski, Angela L., Crowley, Shannon K., Sladek, John R., Maclean, Kenneth N., Bjugstad, Kimberly B.
Опубликовано 2012

Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early stage ethanol-mediated steatosis

по Shearn, Colin T., Smathers, Rebecca L., Jiang, Hua, Orlicky, David J., Maclean, Kenneth N., Petersen, Dennis R.
Опубликовано 2013

A de novo 2.78-Mb duplication on chromosome 21q22.11 implicates candidate genes in the partial trisomy 21 phenotype

по Weisfeld-Adams, James D, Tkachuk, Amanda K, Maclean, Kenneth N, Meeks, Naomi L, Scott, Stuart A
Опубликовано в: NPJ Genom Med (2016)

A de novo 2.78-Mb duplication on chromosome 21q22.11 implicates candidate genes in the partial trisomy 21 phenotype

по Weisfeld-Adams, James D, Tkachuk, Amanda K, Maclean, Kenneth N, Meeks, Naomi L, Scott, Stuart A
Опубликовано в: NPJ Genom Med (2017)

Methylene-tetrahydrofolate reductase contributes to allergic airway disease

по Eyring, Kenneth R., Pedersen, Brent S., Maclean, Kenneth N., Stabler, Sally P., Yang, Ivana V., Schwartz, David A.
Опубликовано в: PLoS One (2018)

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

по Jiang, Hua, Hurt, K. Joseph, Breen, Kelsey, Stabler, Sally P., Allen, Robert H., Orlicky, David J., Maclean, Kenneth N.
Опубликовано в: Biol Open (2015)

The burden of trisomy 21 disrupts the proteostasis network in Down syndrome

по Aivazidis, Stefanos, Coughlan, Christina M., Rauniyar, Abhishek K., Jiang, Hua, Liggett, L. Alexander, Maclean, Kenneth N., Roede, James R.
Опубликовано в: PLoS One (2017)

Analysis of Differential Neonatal Lethality in Cystathionine β-Synthase Deficient Mouse Models using Metabolic Profiling

по Gupta, Sapna, Wang, Liqun, Slifker, Michael J., Cai, Kathy Q., Maclean, Kenneth N., Wasek, Brandi, Bottiglieri, Teodoro, Kruger, Warren D.
Опубликовано в: FASEB J (2021)

Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression

по Quintana, Anita M., Geiger, Elizabeth A., Achilly, Nate, Rosenblatt, David S., Maclean, Kenneth N., Stabler, Sally P., Artinger, Kristin B., Appel, Bruce, Shaikh, Tamim H.
Опубликовано в: Dev Biol (2014)

Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis

по Basseri, Sana, Lhoták, Šárka, Fullerton, Morgan D., Palanivel, Rengasamy, Jiang, Hua, Lynn, Edward G., Ford, Rebecca J., Maclean, Kenneth N., Steinberg, Gregory R., Austin, Richard C.
Опубликовано 2013

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

по Maclean, Kenneth N., Sikora, Jakub, Kožich, Viktor, Jiang, Hua, Greiner, Lori S., Kraus, Eva, Krijt, Jakub, Crnic, Linda S., Allen, Robert H., Stabler, Sally P., Elleder, Milan, Kraus, Jan P.
Опубликовано 2010

SNARE proteins rescue impaired autophagic flux in Down syndrome

по Aivazidis, Stefanos, Jain, Abhilasha, Rauniyar, Abhishek K., Anderson, Colin C., Marentette, John O., Orlicky, David J., Fritz, Kristofer S., Harris, Peter S., Siegel, David, Maclean, Kenneth N., Roede, James R.
Опубликовано в: PLoS One (2019)

Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease

по Gentile, Christopher L., Nivala, Angela M., Gonzales, Jon C., Pfaffenbach, Kyle T., Wang, Dong, Wei, Yuren, Jiang, Hua, Orlicky, David J., Petersen, Dennis R., Pagliassotti, Michael J., Maclean, Kenneth N.
Опубликовано 2011

Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death

по Maclean, Kenneth N., Greiner, Lori S., Evans, Jeffrey R., Sood, Sudesh K., Lhotak, Sarka, Markham, Neil E., Stabler, Sally P., Allen, Robert H., Austin, Richard C., Balasubramaniam, Vivek, Jiang, Hua
Опубликовано 2012

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

по Shearn, Colin T., Orlicky, David J., McCullough, Rebecca L., Jiang, Hua, Maclean, Kenneth N., Mercer, Kelly E., Stiles, Bangyan L., Saba, Laura M., Ronis, Martin J., Petersen, Dennis R.
Опубликовано в: PLoS One (2016)

Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria

по Keating, Amy K., Freehauf, Cynthia, Jiang, Hua, Brodsky, Gary L., Stabler, Sally P., Allen, Robert H., Graham, Douglas K., Thomas, Janet A., Van Hove, Johan L.K., Maclean, Kenneth N.
Опубликовано 2011

GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury

по Platko, Khrystyna, Lebeau, Paul F., Byun, Jae Hyun, Poon, Samantha V., Day, Emily A., MacDonald, Melissa E., Holzapfel, Nicholas, Mejia-Benitez, Aurora, Maclean, Kenneth N., Krepinsky, Joan C., Austin, Richard C.
Опубликовано в: Mol Metab (2019)

Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase: CROSS-TALK BETWEEN INTEGRATED STRESS RESPONSE AND THIOL METABOLISM

по Dickhout, Jeffrey G., Carlisle, Rachel E., Jerome, Danielle E., Mohammed-Ali, Zahraa, Jiang, Hua, Yang, Guangdong, Mani, Sarathi, Garg, Sanjay K., Banerjee, Ruma, Kaufman, Randal J., Maclean, Kenneth N., Wang, Rui, Austin, Richard C.
Опубликовано 2012