Changes in mitochondrial structure and function in 9L rat brain tumor cells treated in vitro with α-difluoromethylornithine, a polyamine biosynthesis inhibitor

Por Oredsson, Stina M., Friend, Daniel S., Marton, Laurence J.
Publicado em 1983

The Polyamine Binding Site in Inward Rectifier K(+) Channels

Por Kurata, Harley T., Marton, Laurence J., Nichols, Colin G.
Publicado em 2006

Polyamine analogues: potent inducers of nucleosomal array oligomerization and inhibitors of yeast cell growth

Por Carruthers, Lenny M., Marton, Laurence J., Peterson, Craig L.
Publicado em 2007

Blocker Protection by Short Spermine Analogs: Refined Mapping of the Spermine Binding Site in a Kir Channel

Por Kurata, Harley T., Diraviyam, Karthikeyan, Marton, Laurence J., Nichols, Colin G.
Publicado em 2008

In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells

Por Hacker, Amy, Marton, Laurence J., Sobolewski, Michelle, Casero, Robert A.
Publicado em 2008

Polyamines in Clinical Disorders

Por Tierney, Donald F., Marton, Laurence J., Hacker, Allen D., Lowe, Nicholas
Publicado em 1985

Polyamine analogues targeting epigenetic gene regulation

Por Huang, Yi, Marton, Laurence J., Woster, Patrick M., Casero, Robert A.
Publicado em 2009

Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes

Por Wu, Yu, Steinbergs, Nora, Murray-Stewart, Tracy, Marton, Laurence J., Casero, Robert A.
Publicado em 2012

Scanning the Topography of Polyamine Blocker Binding in an Inwardly Rectifying Potassium Channel

Por Kurata, Harley T., Akrouh, Alejandro, Li, Jenny B. W., Marton, Laurence J., Nichols, Colin G.
Publicado em 2013

Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism

Por Murray-Stewart, Tracy, Hanigan, Christin L., Woster, Patrick M., Marton, Laurence J., Casero, Robert A.
Publicado em 2013

Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs

Por Roberts, Sigrid C., Jiang, Yuqui, Gasteier, Judith, Frydman, Benjamin, Marton, Laurence J., Heby, Olle, Ullman, Buddy
Publicado em 2007

Therapeutic Evaluation of Polyamine Analogue Drug Candidates against Enterocytozoon bieneusi in a SCID Mouse Model

Por Feng, Xiaochuan, Reddy, Venudhar K., Mayanja-Kizza, Harriet, Weiss, Louis M., Marton, Laurence J., Tzipori, Saul
Publicado em 2009

Polyamine analogues modulate gene expression by inhibiting Lysine-Specific Demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

Por Zhu, Qingsong, Huang, Yi, Marton, Laurence J., Woster, Patrick M., Davidson, Nancy E., Casero, Robert A.
Publicado em 2011

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047

Por Murray-Stewart, Tracy, Ferrari, Elena, Xie, Ying, Yu, Fei, Marton, Laurence J., Oupicky, David, Casero, Robert A.
Publicado no PLoS One (2017)

Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047

Por Murray-Stewart, Tracy, Ferrari, Elena, Xie, Ying, Yu, Fei, Marton, Laurence J., Oupicky, David, Casero, Robert A.
Publicado no PLoS One (2017)

Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy

Por Xie, Ying, Murray-Stewart, Tracy, Wang, Yazhe, Yu, Fei, Li, Jing, Marton, Laurence J., Casero, Robert A., Oupický, David
Publicado no J Control Release (2016)

Gene Expression Analysis of HCT116 Colon Tumor-derived Cells Treated with the Polyamine Analog PG-11047

Por IGNATENKO, NATALIA A., YERUSHALMI, HAGIT F., PANDEY, RITU, KACHEL, KAREN L., STRINGER, DAVID E., MARTON, LAURENCE J., GERNER, EUGENE W.
Publicado em 2009

Role of p53/p21 (Waf1/Cip1) in the Regulation of Polyamine Analogue-Induced Growth Inhibition and Cell Death in Human Breast Cancer Cells

Por Huang, Yi, Pledgie, Allison, Rubin, Ethel, Marton, Laurence J., Woster, Patrick M., Sukumar, Saraswati, Casero, Robert A., Davidson, Nancy E.
Publicado em 2005

Antizyme induction by polyamine analogues as a factor of cell growth inhibition.

Por Mitchell, John L A, Leyser, Aviva, Holtorff, Michelle S, Bates, Jill S, Frydman, Benjamin, Valasinas, Aldonia L, Reddy, Venodhar K, Marton, Laurence J
Publicado em 2002

Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues

Por Bacchi, Cyrus J., Rattendi, Donna, Faciane, Evangeline, Yarlett, Nigel, Weiss, Louis M., Frydman, Benjamin, Woster, Patrick, Wei, Benjamin, Marton, Laurence J., Wittner, Murray
Publicado em 2004