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Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism

The treatment of specific tumor cell lines with poly- and oligoamine analogues results in a super-induction of polyamine catabolism that is associated with cytotoxicity; however, other tumor cells demonstrate resistance to analogue treatment. Recent data indicate that some of these analogues also ha...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Murray-Stewart, Tracy, Hanigan, Christin L., Woster, Patrick M., Marton, Laurence J., Casero, Robert A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808125/
https://ncbi.nlm.nih.gov/pubmed/23943804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0418
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