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Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism

The treatment of specific tumor cell lines with poly- and oligoamine analogues results in a super-induction of polyamine catabolism that is associated with cytotoxicity; however, other tumor cells demonstrate resistance to analogue treatment. Recent data indicate that some of these analogues also ha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Murray-Stewart, Tracy, Hanigan, Christin L., Woster, Patrick M., Marton, Laurence J., Casero, Robert A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808125/
https://ncbi.nlm.nih.gov/pubmed/23943804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0418
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