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Use of Polyamine Derivatives as Selective Histone Deacetylase Inhibitors

Histone acetylation and deacetylation, mediated by histone acetyltransferase and the 11 isoforms of histone deacetylase, play an important role in gene expression. Histone deacetylase inhibitors have found utility in the treatment of cancer by promoting the reexpression of aberrantly silenced genes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Woster, Patrick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925779/
https://ncbi.nlm.nih.gov/pubmed/21318894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-034-8_31
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