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Use of Polyamine Derivatives as Selective Histone Deacetylase Inhibitors
Histone acetylation and deacetylation, mediated by histone acetyltransferase and the 11 isoforms of histone deacetylase, play an important role in gene expression. Histone deacetylase inhibitors have found utility in the treatment of cancer by promoting the reexpression of aberrantly silenced genes...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925779/ https://ncbi.nlm.nih.gov/pubmed/21318894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-034-8_31 |
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