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Blocker Protection by Short Spermine Analogs: Refined Mapping of the Spermine Binding Site in a Kir Channel

Strongly inwardly rectifying potassium channels are blocked by intracellular polyamines with a uniquely steep voltage dependence. An understanding of the fundamental details underlying the voltage dependence of polyamine block requires a constrained structural description of the polyamine-binding si...

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Autors principals: Kurata, Harley T., Diraviyam, Karthikeyan, Marton, Laurence J., Nichols, Colin G.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553148/
https://ncbi.nlm.nih.gov/pubmed/18641062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133256
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