Inhibition of cardiac CaMKII to cure heart failure: step by step towards translation?

Por Cuello, Friederike, Lorenz, Kristina
Publicado no Basic Res Cardiol (2016)

Age-dependent increase in c-Jun N-terminal kinase-2 activity: does this help to understand Ca(2+)-calmodulin-dependent protein-kinase II-mediated atrial arrhythmogenesis in human a...

Por Dobrev, Dobromir, Lorenz, Kristina
Publicado no Cardiovasc Res (2018)

How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency

Por Breitenbach, Tim, Lorenz, Kristina, Dandekar, Thomas
Publicado no Int J Mol Sci (2019)

The A(2B) adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1

Por Koussémou, Marthe, Lorenz, Kristina, Klotz, Karl-Norbert
Publicado no PLoS One (2018)

Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

Por Deiss, Katharina, Kisker, Caroline, Lohse, Martin J., Lorenz, Kristina
Publicado em 2012

Raf kinase inhibitor protein: lessons of a better way for β‐adrenergic receptor activation in the heart

Por Lorenz, Kristina, Rosner, Marsha Rich, Brand, Theresa, Schmitt, Joachim P
Publicado no J Physiol (2017)

β-Adrenoceptor-mediated Relaxation of Urinary Bladder Muscle in β(2)-Adrenoceptor Knockout Mice

Por Propping, Stefan, Lorenz, Kristina, Michel, Martin C., Wirth, Manfred P., Ravens, Ursula
Publicado no Front Pharmacol (2016)

β(1) Adrenoceptor antagonistic effects of the supposedly selective β(2) adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts

Por Pecha, Simon, Flenner, Frederik, Söhren, Klaus-Dieter, Lorenz, Kristina, Eschenhagen, Thomas, Christ, Torsten
Publicado no Pharmacol Res Perspect (2015)

Cardiac amyloidosis mimicking severe aortic valve stenosis – a case report demonstrating diagnostic pitfalls and role of dobutamine stress echocardiography

Por Salinger, Tim, Hu, Kai, Liu, Dan, Herrmann, Sebastian, Lorenz, Kristina, Ertl, Georg, Nordbeck, Peter
Publicado no BMC Cardiovasc Disord (2017)

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

Por Nuber, Susanne, Zabel, Ulrike, Lorenz, Kristina, Nuber, Andreas, Milligan, Graeme, Tobin, Andrew B., Lohse, Martin J., Hoffmann, Carsten
Publicado no Nature (2016)

Interference with ERK(Thr188) phosphorylation impairs pathological but not physiological cardiac hypertrophy

Por Ruppert, Catharina, Deiss, Katharina, Herrmann, Sebastian, Vidal, Marie, Oezkur, Mehmet, Gorski, Armin, Weidemann, Frank, Lohse, Martin J., Lorenz, Kristina
Publicado em 2013

Oral Chaperone Therapy Migalastat for Treating Fabry Disease: Enzymatic Response and Serum Biomarker Changes After 1 Year

Por Müntze, Jonas, Gensler, Daniel, Maniuc, Octavian, Liu, Dan, Cairns, Tereza, Oder, Daniel, Hu, Kai, Lorenz, Kristina, Frantz, Stefan, Wanner, Christoph, Nordbeck, Peter
Publicado no Clin Pharmacol Ther (2019)

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke

Por Schuhmann, Michael K, Kraft, Peter, Stoll, Guido, Lorenz, Kristina, Meuth, Sven G, Wiendl, Heinz, Nieswandt, Bernhard, Sparwasser, Tim, Beyersdorf, Niklas, Kerkau, Thomas, Kleinschnitz, Christoph
Publicado no J Cereb Blood Flow Metab (2015)

Assessing the role of extracellular signal‐regulated kinases 1 and 2 in volume overload‐induced cardiac remodelling

Por Jochmann, Svenja, Elkenani, Manar, Mohamed, Belal A., Buchholz, Eric, Lbik, Dawid, Binder, Lutz, Lorenz, Kristina, Shah, Ajay M., Hasenfuß, Gerd, Toischer, Karl, Schnelle, Moritz
Publicado no ESC Heart Fail (2019)

Association between Comorbidities and Progression of Transvalvular Pressure Gradients in Patients with Moderate and Severe Aortic Valve Stenosis

Por Salinger, Tim, Hu, Kai, Liu, Dan, Taleh, Scharoch, Herrmann, Sebastian, Oder, Daniel, Gensler, Daniel, Müntze, Jonas, Ertl, Georg, Lorenz, Kristina, Frantz, Stefan, Weidemann, Frank, Nordbeck, Peter
Publicado no Cardiol Res Pract (2018)

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

Por Pott, Leona L, Hagemann, Sascha, Reis, Henning, Lorenz, Kristina, Bracht, Thilo, Herold, Thomas, Skryabin, Boris V, Megger, Dominik A, Kälsch, Julia, Weber, Frank, Sitek, Barbara, Baba, Hideo A
Publicado no Oncotarget (2017)

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome

Por Skinner, John J., Wang, Sheng, Lee, Jiyoung, Ong, Colin, Sommese, Ruth, Sivaramakrishnan, Sivaraj, Koelmel, Wolfgang, Hirschbeck, Maria, Schindelin, Hermann, Kisker, Caroline, Lorenz, Kristina, Sosnick, Tobin R., Rosner, Marsha Rich
Publicado no Proc Natl Acad Sci U S A (2017)

Phosphorylation or mutation of the ERK2 activation loop alters oligonucleotide binding

Por McReynolds, Andrea C., Karra, Aroon S., Li, Yan, Lopez, Elias Daniel, Turjanski, Adrian G., Dioum, Elhadji, Lorenz, Kristina, Zaganjor, Elma, Stippec, Steve, McGlynn, Kathleen, Earnest, Svetlana, Cobb, Melanie H.
Publicado no Biochemistry (2016)

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation

Por Schaefer, Andreas, Schneeberger, Yvonne, Schulz, Steven, Krasemann, Susanne, Werner, Tessa, Piasecki, Angelika, Höppner, Grit, Müller, Christian, Morhenn, Karoline, Lorenz, Kristina, Wieczorek, David, Schwoerer, Alexander P., Eschenhagen, Thomas, Ehmke, Heimo, Reichenspurner, Hermann, Stenzig, Justus, Cuello, Friederike
Publicado no Sci Rep (2019)

Biochemical and pathological changes result from mutated Caveolin-3 in muscle

Por González Coraspe, José Andrés, Weis, Joachim, Anderson, Mary E., Münchberg, Ute, Lorenz, Kristina, Buchkremer, Stephan, Carr, Stephanie, Zahedi, René Peiman, Brauers, Eva, Michels, Hannah, Sunada, Yoshihide, Lochmüller, Hanns, Campbell, Kevin P., Freier, Erik, Hathazi, Denisa, Roos, Andreas
Publicado no Skelet Muscle (2018)