β(1) Adrenoceptor antagonistic effects of the supposedly selective β(2) adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts

Studies on the relative contribution of β(1)- and β(2)-adrenoceptors (AR) generally employ selective β(1)- and β(2)-AR antagonists such as CGP 20712A and ICI 118,551, respectively, and assume that antagonism by one of these compounds indicates mediation by the respective AR subtype. Here, we evaluat...

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Detalles Bibliográficos
Publicado en:Pharmacol Res Perspect
Main Authors: Pecha, Simon, Flenner, Frederik, Söhren, Klaus-Dieter, Lorenz, Kristina, Eschenhagen, Thomas, Christ, Torsten
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618639/
https://ncbi.nlm.nih.gov/pubmed/26516580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.168
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