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β(1) Adrenoceptor antagonistic effects of the supposedly selective β(2) adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts
Studies on the relative contribution of β(1)- and β(2)-adrenoceptors (AR) generally employ selective β(1)- and β(2)-AR antagonists such as CGP 20712A and ICI 118,551, respectively, and assume that antagonism by one of these compounds indicates mediation by the respective AR subtype. Here, we evaluat...
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Izdano u: | Pharmacol Res Perspect |
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Glavni autori: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
John Wiley & Sons, Ltd
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618639/ https://ncbi.nlm.nih.gov/pubmed/26516580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.168 |
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