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Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome
Phosphorylation is a major regulator of protein interactions; however, the mechanisms by which regulation occurs are not well understood. Here we identify a salt-bridge competition or “theft” mechanism that enables a phospho-triggered swap of protein partners by Raf Kinase Inhibitory Protein (RKIP)....
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| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754776/ https://ncbi.nlm.nih.gov/pubmed/29208709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711543114 |
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