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The A(2B) adenosine receptor in MDA-MB-231 breast cancer cells diminishes ERK1/2 phosphorylation by activation of MAPK-phosphatase-1

It was previously shown that the estrogen-receptor negative breast cancer cell line MBA-MD-231 expresses high levels of A(2B) adenosine receptors as the sole adenosine receptor subtype. These receptors couple to both, stimulation of adenylyl cyclase and a Ca(2+) signal. In order to establish a poten...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Koussémou, Marthe, Lorenz, Kristina, Klotz, Karl-Norbert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114864/
https://ncbi.nlm.nih.gov/pubmed/30157211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202914
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