Emerging anti-cancer antibodies and combination therapies targeting HER3/ERBB3

af Gaborit, Nadège, Lindzen, Moshit, Yarden, Yosef
Udgivet i Hum Vaccin Immunother (2015)

Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands

af Lindzen, Moshit, Lavi, Sara, Leitner, Orith, Yarden, Yosef
Udgivet 2010

Database-independent Protein Sequencing (DiPS) Enables Full-length de Novo Protein and Antibody Sequence Determination

af Savidor, Alon, Barzilay, Rotem, Elinger, Dalia, Yarden, Yosef, Lindzen, Moshit, Gabashvili, Alexandra, Adiv Tal, Ophir, Levin, Yishai
Udgivet i Mol Cell Proteomics (2017)

A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy

af Gelfo, Valerio, Mazzeschi, Martina, Grilli, Giada, Lindzen, Moshit, Santi, Spartaco, D’Uva, Gabriele, Győrffy, Balázs, Ardizzoni, Andrea, Yarden, Yosef, Lauriola, Mattia
Udgivet i Cancers (Basel) (2018)

A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis

af Lindzen, Moshit, Carvalho, Silvia, Starr, Alex, Ben-Chetrit, Nir, Pradeep, Chaluvally-Raghavan, Köstler, Wolfgang J., Rabinkov, Aaron, Lavi, Sara, Bacus, Sarah S., Yarden, Yosef
Udgivet 2011

Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR

af Ferraro, Daniela A., Gaborit, Nadège, Maron, Ruth, Cohen-Dvashi, Hadas, Porat, Ziv, Pareja, Fresia, Lavi, Sara, Lindzen, Moshit, Ben-Chetrit, Nir, Sela, Michael, Yarden, Yosef
Udgivet 2013

Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models

af Marrocco, Ilaria, Romaniello, Donatella, Vaknin, Itay, Drago‐Garcia, Diana, Oren, Roni, Uribe, Mary Luz, Belugali Nataraj, Nishanth, Ghosh, Soma, Eilam, Raya, Salame, Tomer‐Meir, Lindzen, Moshit, Yarden, Yosef
Udgivet i EMBO Mol Med (2021)

Host-dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors

af Haga, Yuya, Marrocco, Ilaria, Noronha, Ashish, Uribe, Mary Luz, Nataraj, Nishanth Belugali, Sekar, Arunachalam, Drago-Garcia, Diana, Borgoni, Simone, Lindzen, Moshit, Giri, Suvendu, Wiemann, Stefan, Tsutsumi, Yasuo, Yarden, Yosef
Udgivet i Cancer Res (2021)

Examination of HER3 targeting in cancer using monoclonal antibodies

af Gaborit, Nadège, Abdul-Hai, Ali, Mancini, Maicol, Lindzen, Moshit, Lavi, Sara, Leitner, Orith, Mounier, Lucile, Chentouf, Myriam, Dunoyer, Sai, Ghosh, Manjusha, Larbouret, Christel, Chardès, Thierry, Bazin, Hervé, Pèlegrin, André, Sela, Michael, Yarden, Yosef
Udgivet i Proc Natl Acad Sci U S A (2015)

A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors

af Gelfo, Valerio, Rodia, Maria Teresa, Pucci, Michela, Dall'Ora, Massimiliano, Santi, Spartaco, Solmi, Rossella, Roth, Lee, Lindzen, Moshit, Bonafè, Massimiliano, Bertotti, Andrea, Caramelli, Elisabetta, Lollini, Pier-Luigi, Trusolino, Livio, Yarden, Yosef, D'Uva, Gabriele, Lauriola, Mattia
Udgivet i Oncotarget (2016)

Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53

af Lindzen, Moshit, Ghosh, Soma, Noronha, Ashish, Drago, Diana, Nataraj, Nishanth Belugali, Leitner, Orith, Carvalho, Silvia, Zmora, Einav, Sapoznik, Stav, Shany, Keren Bahar, Levanon, Keren, Aderka, Dan, Ramírez, Belinda Sánchez, Dahlhoff, Maik, McNeish, Iain, Yarden, Yosef
Udgivet i Oncogene (2021)

Targeting HER3, a Catalytically Defective Receptor Tyrosine Kinase, Prevents Resistance of Lung Cancer to a Third-Generation EGFR Kinase Inhibitor

af Romaniello, Donatella, Marrocco, Ilaria, Belugali Nataraj, Nishanth, Ferrer, Irene, Drago-Garcia, Diana, Vaknin, Itay, Oren, Roni, Lindzen, Moshit, Ghosh, Soma, Kreitman, Matthew, Kittel, Jeanette Clarissa, Gaborit, Nadege, Bergado Baez, Gretchen, Sanchez, Belinda, Eilam, Raya, Pikarsky, Eli, Paz-Ares, Luis, Yarden, Yosef
Udgivet i Cancers (Basel) (2020)

Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone

af Enuka, Yehoshua, Feldman, Morris E., Chowdhury, Animesh, Srivastava, Swati, Lindzen, Moshit, Sas-Chen, Aldema, Massart, Renaud, Cheishvili, David, Suderman, Matthew J., Zaltsman, Yoav, Mazza, Chiara A., Shukla, Kirti, Körner, Cindy, Furth, Noa, Lauriola, Mattia, Oren, Moshe, Wiemann, Stefan, Szyf, Moshe, Yarden, Yosef
Udgivet i Nucleic Acids Res (2017)

An oligoclonal antibody durably overcomes resistance of lung cancer to third‐generation EGFR inhibitors

af Mancini, Maicol, Gal, Hilah, Gaborit, Nadège, Mazzeo, Luigi, Romaniello, Donatella, Salame, Tomer Meir, Lindzen, Moshit, Mahlknecht, Georg, Enuka, Yehoshua, Burton, Dominick GA, Roth, Lee, Noronha, Ashish, Marrocco, Ilaria, Adreka, Dan, Altstadter, Raya Eilam, Bousquet, Emilie, Downward, Julian, Maraver, Antonio, Krizhanovsky, Valery, Yarden, Yosef
Udgivet i EMBO Mol Med (2017)

Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

af Lauriola, Mattia, Enuka, Yehoshua, Zeisel, Amit, D’Uva, Gabriele, Roth, Lee, Sharon-Sevilla, Michal, Lindzen, Moshit, Sharma, Kirti, Nevo, Nava, Feldman, Morris, Carvalho, Silvia, Cohen-Dvashi, Hadas, Kedmi, Merav, Ben-Chetrit, Nir, Chen, Alon, Solmi, Rossella, Wiemann, Stefan, Schmitt, Fernando, Domany, Eytan, Yarden, Yosef
Udgivet 2014

PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR

af Ghosh, Soma, Nataraj, Nishanth Belugali, Noronha, Ashish, Patkar, Sushant, Sekar, Arunachalam, Mukherjee, Saptaparna, Winograd-Katz, Sabina, Kramarski, Lior, Verma, Aakanksha, Lindzen, Moshit, Garcia, Diana Drago, Green, Joseph, Eisenberg, Galit, Gil-Henn, Hava, Basu, Arkaprabha, Lender, Yan, Weiss, Shimon, Oren, Moshe, Lotem, Michal, Geiger, Benjamin, Ruppin, Eytan, Yarden, Yosef
Udgivet i Cell Rep (2021)

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer

af Kubli, Shawn P., Bassi, Christian, Roux, Cecilia, Wakeham, Andrew, Göbl, Christoph, Zhou, Wenjing, Jafari, Soode Moghadas, Snow, Bryan, Jones, Lisa, Palomero, Luis, Thu, Kelsie L., Cassetta, Luca, Soong, Daniel, Berger, Thorsten, Ramachandran, Parameswaran, Baniasadi, Shakiba P., Duncan, Gordon, Lindzen, Moshit, Yarden, Yosef, Herranz, Carmen, Lazaro, Conxi, Chu, Mandy F., Haight, Jillian, Tinto, Paul, Silvester, Jennifer, Cescon, David W., Petit, Anna, Pettersson, Sven, Pollard, Jeffrey W., Mak, Tak W., Pujana, Miguel A., Cappello, Paola, Gorrini, Chiara
Udgivet i Proc Natl Acad Sci U S A (2019)