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A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis
EGF-like growth factors control tumor progression, as well as evasion from the toxic effects of chemotherapy. Accordingly, antibodies targeting the cognate receptors, such as EGFR/ErbB-1 and the co-receptor HER2/ErbB-2, are widely used to treat cancer patients, but agents that target the EGF-like gr...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290749/ https://ncbi.nlm.nih.gov/pubmed/22105361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.518 |
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