A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis

EGF-like growth factors control tumor progression, as well as evasion from the toxic effects of chemotherapy. Accordingly, antibodies targeting the cognate receptors, such as EGFR/ErbB-1 and the co-receptor HER2/ErbB-2, are widely used to treat cancer patients, but agents that target the EGF-like gr...

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Huvudupphovsmän: Lindzen, Moshit, Carvalho, Silvia, Starr, Alex, Ben-Chetrit, Nir, Pradeep, Chaluvally-Raghavan, Köstler, Wolfgang J., Rabinkov, Aaron, Lavi, Sara, Bacus, Sarah S., Yarden, Yosef
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290749/
https://ncbi.nlm.nih.gov/pubmed/22105361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.518
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