Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

Signal transduction by receptor tyrosine kinases (RTKs) and nuclear receptors for steroid hormones is essential for body homeostasis, but the cross-talk between these receptor families is poorly understood. We observed that glucocorticoids inhibit signalling downstream of EGFR, an RTK. The underlyin...

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Detaylı Bibliyografya
Asıl Yazarlar: Lauriola, Mattia, Enuka, Yehoshua, Zeisel, Amit, D’Uva, Gabriele, Roth, Lee, Sharon-Sevilla, Michal, Lindzen, Moshit, Sharma, Kirti, Nevo, Nava, Feldman, Morris, Carvalho, Silvia, Cohen-Dvashi, Hadas, Kedmi, Merav, Ben-Chetrit, Nir, Chen, Alon, Solmi, Rossella, Wiemann, Stefan, Schmitt, Fernando, Domany, Eytan, Yarden, Yosef
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205848/
https://ncbi.nlm.nih.gov/pubmed/25278152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6073
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