Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes

Por Danilova, Tatiana, Lindahl, Maria
Publicado no Front Physiol (2018)

MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex

Por Tseng, Kuan-Yin, Danilova, Tatiana, Domanskyi, Andrii, Saarma, Mart, Lindahl, Maria, Airavaara, Mikko
Publicado no eNeuro (2017)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function

Por Danilova, Tatiana, Galli, Emilia, Pakarinen, Emmi, Palm, Erik, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria
Publicado no Front Endocrinol (Lausanne) (2019)

Neuroplastin Modulates Anti-inflammatory Effects of MANF

Por Yagi, Takuya, Asada, Rie, Kanekura, Kohsuke, Eesmaa, Ave, Lindahl, Maria, Saarma, Mart, Urano, Fumihiko
Publicado no iScience (2020)

Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss

Por Herranen, Anni, Ikäheimo, Kuu, Lankinen, Tuuli, Pakarinen, Emmi, Fritzsch, Bernd, Saarma, Mart, Lindahl, Maria, Pirvola, Ulla
Publicado no Cell Death Dis (2020)

MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System

Por Pakarinen, Emmi, Danilova, Tatiana, Võikar, Vootele, Chmielarz, Piotr, Piepponen, Petteri, Airavaara, Mikko, Saarma, Mart, Lindahl, Maria
Publicado no eNeuro (2020)

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke

Por Tseng, Kuan-Yin, Anttila, Jenni E., Khodosevich, Konstantin, Tuominen, Raimo K., Lindahl, Maria, Domanskyi, Andrii, Airavaara, Mikko
Publicado no Mol Ther (2018)

The role of the CCR1 receptor in the inflammatory response to tobacco smoke in a mouse model

Por Önnervik, Per-Ola, Lindahl, Maria, Svitacheva, Naila, Stämpfli, Martin, Thim, Kerstin, Smailagic, Amir, Virtala, Robert, Taylor, John D.
Publicado em 2010

Gfra1 Underexpression Causes Hirschsprung’s Disease and Associated Enterocolitis in Mice

Por Porokuokka, L. Lauriina, Virtanen, Heikki T., Lindén, Jere, Sidorova, Yulia, Danilova, Tatiana, Lindahl, Maria, Saarma, Mart, Andressoo, Jaan-Olle
Publicado no Cell Mol Gastroenterol Hepatol (2018)

Mesencephalic Astrocyte–Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress–Related Kidney Diseases

Por Kim, Yeawon, Lee, Heedoo, Manson, Scott R., Lindahl, Maria, Evans, Bradley, Miner, Jeffrey H., Urano, Fumihiko, Chen, Ying Maggie
Publicado no J Am Soc Nephrol (2016)

Secondary Structure Changes in ApoA-I Milano (R173C) Are Not Accompanied by a Decrease in Protein Stability or Solubility

Por Petrlova, Jitka, Dalla-Riva, Jonathan, Mörgelin, Matthias, Lindahl, Maria, Krupinska, Ewa, Stenkula, Karin G., Voss, John C., Lagerstedt, Jens O.
Publicado em 2014

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

Por Park, Sun-Ji, Kim, Yeawon, Yang, Shyh-Ming, Henderson, Mark J., Yang, Wei, Lindahl, Maria, Urano, Fumihiko, Chen, Ying Maggie
Publicado no Proc Natl Acad Sci U S A (2019)

Cerebral Dopamine Neurotrophic Factor Is Essential for Enteric Neuronal Development, Maintenance and Regulation of Gastrointestinal Transit

Por Chalazonitis, Alcmène, Li, ZhiShan, Pham, Tuan D., Chen, Jason, Rao, Meenakshi, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria, Gershon, Michael D.
Publicado no J Comp Neurol (2020)

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

Por Galli, Emilia, Härkönen, Taina, Sainio, Markus T., Ustav, Mart, Toots, Urve, Urtti, Arto, Yliperttula, Marjo, Lindahl, Maria, Knip, Mikael, Saarma, Mart, Lindholm, Päivi
Publicado no Sci Rep (2016)

Single injections of apoA-I acutely improve in vivo glucose tolerance in insulin-resistant mice

Por Stenkula, Karin G., Lindahl, Maria, Petrlova, Jitka, Dalla-Riva, Jonathan, Göransson, Olga, Cushman, Samuel W., Krupinska, Ewa, Jones, Helena A., Lagerstedt, Jens O.
Publicado em 2014

CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice

Por Airavaara, Mikko, Harvey, Brandon K, Voutilainen, Merja H., Shen, Hui, Chou, Jenny, Lindholm, Päivi, Lindahl, Maria, Tuominen, Raimo K., Saarma, Mart, Wang, Yun, Hoffer, Barry
Publicado em 2011

Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra

Por Mätlik, Kert, Vihinen, Helena, Bienemann, Ali, Palgi, Jaan, Voutilainen, Merja H., Booms, Sigrid, Lindahl, Maria, Jokitalo, Eija, Saarma, Mart, Huttunen, Henri J., Airavaara, Mikko, Arumäe, Urmas
Publicado no eNeuro (2017)

MANF is indispensable for the proliferation and survival of pancreatic β-cells

Por Lindahl, Maria, Danilova, Tatiana, Palm, Erik, Lindholm, Päivi, Võikar, Vootele, Hakonen, Elina, Ustinov, Jarkko, Andressoo, Jaan-Olle, Harvey, Brandon K., Otonkoski, Timo, Rossi, Jari, Saarma, Mart
Publicado no Cell Rep (2014)

Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)

Por Cunha, Daniel A., Cito, Monia, Grieco, Fabio Arturo, Cosentino, Cristina, Danilova, Tatiana, Ladrière, Laurence, Lindahl, Maria, Domanskyi, Andrii, Bugliani, Marco, Marchetti, Piero, Eizirik, Décio L., Cnop, Miriam
Publicado no J Biol Chem (2017)

Poststroke delivery of MANF promotes functional recovery in rats

Por Mätlik, Kert, Anttila, Jenni E., Kuan-Yin, Tseng, Smolander, Olli-Pekka, Pakarinen, Emmi, Lehtonen, Leevi, Abo-Ramadan, Usama, Lindholm, Päivi, Zheng, Congjun, Harvey, Brandon, Arumäe, Urmas, Lindahl, Maria, Airavaara, Mikko
Publicado no Sci Adv (2018)