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Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra

Cerebral dopamine neurotrophic factor (CDNF) protects the nigrostriatal dopaminergic (DA) neurons in rodent models of Parkinson’s disease and restores DA circuitry when delivered after these neurons have begun to degenerate. These DA neurons have been suggested to transport striatal CDNF retrogradel...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Mätlik, Kert, Vihinen, Helena, Bienemann, Ali, Palgi, Jaan, Voutilainen, Merja H., Booms, Sigrid, Lindahl, Maria, Jokitalo, Eija, Saarma, Mart, Huttunen, Henri J., Airavaara, Mikko, Arumäe, Urmas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318544/
https://ncbi.nlm.nih.gov/pubmed/28275710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0128-16.2017
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