Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra

Cerebral dopamine neurotrophic factor (CDNF) protects the nigrostriatal dopaminergic (DA) neurons in rodent models of Parkinson’s disease and restores DA circuitry when delivered after these neurons have begun to degenerate. These DA neurons have been suggested to transport striatal CDNF retrogradel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eNeuro
Prif Awduron: Mätlik, Kert, Vihinen, Helena, Bienemann, Ali, Palgi, Jaan, Voutilainen, Merja H., Booms, Sigrid, Lindahl, Maria, Jokitalo, Eija, Saarma, Mart, Huttunen, Henri J., Airavaara, Mikko, Arumäe, Urmas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2017
Pynciau:
New Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318544/
https://ncbi.nlm.nih.gov/pubmed/28275710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0128-16.2017
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