Efficacy, patterns of use and cost of Pertuzumab in the treatment of HER2+ metastatic breast cancer in Singapore: The National Cancer Centre Singapore experience

Bằng Rahardja, Sylwan, Tan, Ryan Ying Cong, Sultana, Rehena, Leong, Fun Loon, Lim, Elaine Hsuen
Xuất bản năm World J Clin Oncol (2020)

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

Bằng Chan, Yingleong, Chan, Ying Kai, Goodman, Daniel B., Guo, Xiaoge, Chavez, Alejandro, Lim, Elaine T., Church, George M.
Xuất bản năm Genome Med (2018)

Germline Mutations Affecting Gα(11) in Hypoparathyroidism

Bằng Mannstadt, Michael, Harris, Mark, Bravenboer, Bert, Chitturi, Sridhar, Dreijerink, Koen M.A., Lambright, David G., Lim, Elaine T., Daly, Mark J., Gabriel, Stacey, Jüppner, Harald
Được phát hành 2013

CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination

Bằng Ravindranath, Abhilash K., Kaur, Swayamjot, Wernyj, Roman P., Kumaran, Muthu N., Miletti-Gonzalez, Karl E., Chan, Rigel, Lim, Elaine, Madura, Kiran, Rodriguez-Rodriguez, Lorna
Xuất bản năm Oncotarget (2015)

Image Analysis Using Machine Learning for Automated Detection of Hemoglobin H Inclusions in Blood Smears – A Method for Morphologic Detection of Rare Cells

Bằng Lee, Shir Ying, Chen, Crystal M. E., Lim, Elaine Y. P., Shen, Liang, Sathe, Aneesh, Singh, Aahan, Sauer, Jan, Taghipour, Kaveh, Yip, Christina Y. C.
Xuất bản năm J Pathol Inform (2021)

An Excess of Risk-Increasing Low-Frequency Variants Can Be a Signal of Polygenic Inheritance in Complex Diseases

Bằng Chan, Yingleong, Lim, Elaine T., Sandholm, Niina, Wang, Sophie R., McKnight, Amy Jayne, Ripke, Stephan, Daly, Mark J., Neale, Benjamin M., Salem, Rany M., Hirschhorn, Joel N.
Được phát hành 2014

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

Bằng Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Xuất bản năm Eur J Hum Genet (2015)

An unbiased index to quantify participant’s phenotypic contribution to an open-access cohort

Bằng Chan, Yingleong, Tung, Michael, Garruss, Alexander S., Zaranek, Sarah W., Chan, Ying Kai, Lunshof, Jeantine E., Zaranek, Alexander W., Ball, Madeleine P., Chou, Michael F., Lim, Elaine T., Church, George M.
Xuất bản năm Sci Rep (2017)

Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism

Bằng Chahrour, Maria H., Yu, Timothy W., Lim, Elaine T., Ataman, Bulent, Coulter, Michael E., Hill, R. Sean, Stevens, Christine R., Schubert, Christian R., Greenberg, Michael E., Gabriel, Stacey B., Walsh, Christopher A.
Được phát hành 2012

A Novel Test for Recessive Contributions to Complex Diseases Implicates Bardet-Biedl Syndrome Gene BBS10 in Idiopathic Type 2 Diabetes and Obesity

Bằng Lim, Elaine T., Liu, Yangfan P., Chan, Yingleong, Tiinamaija, Tuomi, Käräjämäki, AnnMari, Madsen, Erik, Altshuler, David M., Raychaudhuri, Soumya, Groop, Leif, Flannick, Jason, Hirschhorn, Joel N., Katsanis, Nicholas, Daly, Mark J.
Xuất bản năm Am J Hum Genet (2014)

DGAT1 mutation is linked to a congenital diarrheal disorder

Bằng Haas, Joel T., Winter, Harland S., Lim, Elaine, Kirby, Andrew, Blumenstiel, Brendan, DeFelice, Matthew, Gabriel, Stacey, Branski, David, Grueter, Carrie A., Toporovski, Mauro S., Walther, Tobias C., Daly, Mark J., Farese, Robert V., Jalas, Chaim
Được phát hành 2012

Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes

Bằng He, Xin, Sanders, Stephan J., Liu, Li, De Rubeis, Silvia, Lim, Elaine T., Sutcliffe, James S., Schellenberg, Gerard D., Gibbs, Richard A., Daly, Mark J., Buxbaum, Joseph D., State, Matthew W., Devlin, Bernie, Roeder, Kathryn
Được phát hành 2013

High Densities of Tumor-Associated Plasma Cells Predict Improved Prognosis in Triple Negative Breast Cancer

Bằng Yeong, Joe, Lim, Jeffrey Chun Tatt, Lee, Bernett, Li, Huihua, Chia, Noel, Ong, Clara Chong Hui, Lye, Weng Kit, Putti, Thomas Choudary, Dent, Rebecca, Lim, Elaine, Thike, Aye Aye, Tan, Puay Hoon, Iqbal, Jabed
Xuất bản năm Front Immunol (2018)

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

Bằng Chan, Yingleong, Salem, Rany M., Hsu, Yu-Han H., McMahon, George, Pers, Tune H., Vedantam, Sailaja, Esko, Tonu, Guo, Michael H., Lim, Elaine T., Franke, Lude, Smith, George Davey, Strachan, David P., Hirschhorn, Joel N.
Xuất bản năm Am J Hum Genet (2015)

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Bằng Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C., Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Xuất bản năm Cell Rep (2019)

Recessive gene disruptions in autism spectrum disorder

Bằng Doan, Ryan N, Lim, Elaine T., De Rubeis, Silvia, Betancur, Catalina, Cutler, David J., Chiocchetti, Andreas G., Overman, Lynne M., Soucy, Aubrie, Goetze, Susanne, Freitag, Christine M., Daly, Mark J., Walsh, Christopher A., Buxbaum, Joseph D., Yu, Timothy W.
Xuất bản năm Nat Genet (2019)

A Homozygous Mutation in KCTD7 Links Neuronal Ceroid Lipofuscinosis to the Ubiquitin-Proteasome System

Bằng Staropoli, John F., Karaa, Amel, Lim, Elaine T., Kirby, Andrew, Elbalalesy, Naser, Romansky, Stephen G., Leydiker, Karen B., Coppel, Scott H., Barone, Rosemary, Xin, Winnie, MacDonald, Marcy E., Abdenur, Jose E., Daly, Mark J., Sims, Katherine B., Cotman, Susan L.
Được phát hành 2012

Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD): MODULATION OF MATRIX METALLOPROTEINASE 9 (MMP-9) TRANSCRIPTION VIA NOVEL PROMOTER RESPONSE ELEMENT

Bằng Miletti-González, Karl E., Murphy, Kyle, Kumaran, Muthu N., Ravindranath, Abhilash K., Wernyj, Roman P., Kaur, Swayamjot, Miles, Gregory D., Lim, Elaine, Chan, Rigel, Chekmareva, Marina, Heller, Debra S., Foran, David, Chen, Wenjin, Reiss, Michael, Bandera, Elisa V., Scotto, Kathleen, Rodríguez-Rodríguez, Lorna
Được phát hành 2012

Detection and prognostic relevance of circulating tumour cells (CTCs) in Asian breast cancers using a label-free microfluidic platform

Bằng Yap, Yoon-Sim, Leong, Man Chun, Chua, Yong Wei, Loh, Kiley Wei Jen, Lee, Guek Eng, Lim, Elaine Hsuen, Dent, Rebecca, Ng, Raymond Chee Hui, Lim, John Heng-Chi, Singh, Garima, Tan, Angela, Guan, Guofeng, Wu, Andrew, Lee, Yi Fang, Bhagat, Ali Asgar S., Lim, Darren Wan-Teck
Xuất bản năm PLoS One (2019)

An enhanced CRISPR repressor for targeted mammalian gene regulation

Bằng Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T, Davidsohn, Noah, Ebrahimkhani, Mo R., Collins, James J., Lewis, Nathan E., Kiani, Samira, Church, George M.
Xuất bản năm Nat Methods (2018)