Efficacy, patterns of use and cost of Pertuzumab in the treatment of HER2+ metastatic breast cancer in Singapore: The National Cancer Centre Singapore experience

by Rahardja, Sylwan, Tan, Ryan Ying Cong, Sultana, Rehena, Leong, Fun Loon, Lim, Elaine Hsuen
Published in World J Clin Oncol (2020)

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

by Chan, Yingleong, Chan, Ying Kai, Goodman, Daniel B., Guo, Xiaoge, Chavez, Alejandro, Lim, Elaine T., Church, George M.
Published in Genome Med (2018)

Germline Mutations Affecting Gα(11) in Hypoparathyroidism

by Mannstadt, Michael, Harris, Mark, Bravenboer, Bert, Chitturi, Sridhar, Dreijerink, Koen M.A., Lambright, David G., Lim, Elaine T., Daly, Mark J., Gabriel, Stacey, Jüppner, Harald
Published 2013

CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination

by Ravindranath, Abhilash K., Kaur, Swayamjot, Wernyj, Roman P., Kumaran, Muthu N., Miletti-Gonzalez, Karl E., Chan, Rigel, Lim, Elaine, Madura, Kiran, Rodriguez-Rodriguez, Lorna
Published in Oncotarget (2015)

Image Analysis Using Machine Learning for Automated Detection of Hemoglobin H Inclusions in Blood Smears – A Method for Morphologic Detection of Rare Cells

by Lee, Shir Ying, Chen, Crystal M. E., Lim, Elaine Y. P., Shen, Liang, Sathe, Aneesh, Singh, Aahan, Sauer, Jan, Taghipour, Kaveh, Yip, Christina Y. C.
Published in J Pathol Inform (2021)

An Excess of Risk-Increasing Low-Frequency Variants Can Be a Signal of Polygenic Inheritance in Complex Diseases

by Chan, Yingleong, Lim, Elaine T., Sandholm, Niina, Wang, Sophie R., McKnight, Amy Jayne, Ripke, Stephan, Daly, Mark J., Neale, Benjamin M., Salem, Rany M., Hirschhorn, Joel N.
Published 2014

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

by Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Published in Eur J Hum Genet (2015)

An unbiased index to quantify participant’s phenotypic contribution to an open-access cohort

by Chan, Yingleong, Tung, Michael, Garruss, Alexander S., Zaranek, Sarah W., Chan, Ying Kai, Lunshof, Jeantine E., Zaranek, Alexander W., Ball, Madeleine P., Chou, Michael F., Lim, Elaine T., Church, George M.
Published in Sci Rep (2017)

Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism

by Chahrour, Maria H., Yu, Timothy W., Lim, Elaine T., Ataman, Bulent, Coulter, Michael E., Hill, R. Sean, Stevens, Christine R., Schubert, Christian R., Greenberg, Michael E., Gabriel, Stacey B., Walsh, Christopher A.
Published 2012

A Novel Test for Recessive Contributions to Complex Diseases Implicates Bardet-Biedl Syndrome Gene BBS10 in Idiopathic Type 2 Diabetes and Obesity

by Lim, Elaine T., Liu, Yangfan P., Chan, Yingleong, Tiinamaija, Tuomi, Käräjämäki, AnnMari, Madsen, Erik, Altshuler, David M., Raychaudhuri, Soumya, Groop, Leif, Flannick, Jason, Hirschhorn, Joel N., Katsanis, Nicholas, Daly, Mark J.
Published in Am J Hum Genet (2014)

DGAT1 mutation is linked to a congenital diarrheal disorder

by Haas, Joel T., Winter, Harland S., Lim, Elaine, Kirby, Andrew, Blumenstiel, Brendan, DeFelice, Matthew, Gabriel, Stacey, Branski, David, Grueter, Carrie A., Toporovski, Mauro S., Walther, Tobias C., Daly, Mark J., Farese, Robert V., Jalas, Chaim
Published 2012

Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes

by He, Xin, Sanders, Stephan J., Liu, Li, De Rubeis, Silvia, Lim, Elaine T., Sutcliffe, James S., Schellenberg, Gerard D., Gibbs, Richard A., Daly, Mark J., Buxbaum, Joseph D., State, Matthew W., Devlin, Bernie, Roeder, Kathryn
Published 2013

High Densities of Tumor-Associated Plasma Cells Predict Improved Prognosis in Triple Negative Breast Cancer

by Yeong, Joe, Lim, Jeffrey Chun Tatt, Lee, Bernett, Li, Huihua, Chia, Noel, Ong, Clara Chong Hui, Lye, Weng Kit, Putti, Thomas Choudary, Dent, Rebecca, Lim, Elaine, Thike, Aye Aye, Tan, Puay Hoon, Iqbal, Jabed
Published in Front Immunol (2018)

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

by Chan, Yingleong, Salem, Rany M., Hsu, Yu-Han H., McMahon, George, Pers, Tune H., Vedantam, Sailaja, Esko, Tonu, Guo, Michael H., Lim, Elaine T., Franke, Lude, Smith, George Davey, Strachan, David P., Hirschhorn, Joel N.
Published in Am J Hum Genet (2015)

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

by Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C., Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Published in Cell Rep (2019)

Recessive gene disruptions in autism spectrum disorder

by Doan, Ryan N, Lim, Elaine T., De Rubeis, Silvia, Betancur, Catalina, Cutler, David J., Chiocchetti, Andreas G., Overman, Lynne M., Soucy, Aubrie, Goetze, Susanne, Freitag, Christine M., Daly, Mark J., Walsh, Christopher A., Buxbaum, Joseph D., Yu, Timothy W.
Published in Nat Genet (2019)

A Homozygous Mutation in KCTD7 Links Neuronal Ceroid Lipofuscinosis to the Ubiquitin-Proteasome System

by Staropoli, John F., Karaa, Amel, Lim, Elaine T., Kirby, Andrew, Elbalalesy, Naser, Romansky, Stephen G., Leydiker, Karen B., Coppel, Scott H., Barone, Rosemary, Xin, Winnie, MacDonald, Marcy E., Abdenur, Jose E., Daly, Mark J., Sims, Katherine B., Cotman, Susan L.
Published 2012

Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD): MODULATION OF MATRIX METALLOPROTEINASE 9 (MMP-9) TRANSCRIPTION VIA NOVEL PROMOTER RESPONSE ELEMENT

by Miletti-González, Karl E., Murphy, Kyle, Kumaran, Muthu N., Ravindranath, Abhilash K., Wernyj, Roman P., Kaur, Swayamjot, Miles, Gregory D., Lim, Elaine, Chan, Rigel, Chekmareva, Marina, Heller, Debra S., Foran, David, Chen, Wenjin, Reiss, Michael, Bandera, Elisa V., Scotto, Kathleen, Rodríguez-Rodríguez, Lorna
Published 2012

Detection and prognostic relevance of circulating tumour cells (CTCs) in Asian breast cancers using a label-free microfluidic platform

by Yap, Yoon-Sim, Leong, Man Chun, Chua, Yong Wei, Loh, Kiley Wei Jen, Lee, Guek Eng, Lim, Elaine Hsuen, Dent, Rebecca, Ng, Raymond Chee Hui, Lim, John Heng-Chi, Singh, Garima, Tan, Angela, Guan, Guofeng, Wu, Andrew, Lee, Yi Fang, Bhagat, Ali Asgar S., Lim, Darren Wan-Teck
Published in PLoS One (2019)

An enhanced CRISPR repressor for targeted mammalian gene regulation

by Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T, Davidsohn, Noah, Ebrahimkhani, Mo R., Collins, James J., Lewis, Nathan E., Kiani, Samira, Church, George M.
Published in Nat Methods (2018)