Understanding the Roles of the Kynurenine Pathway in Multiple Sclerosis Progression

Por Lim, Chai K., Brew, Bruce J., Sundaram, Gayathri, Guillemin, Gilles J.
Publicado em 2010

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

Por Heng, Benjamin, Lim, Chai K., Lovejoy, David B., Bessede, Alban, Gluch, Laurence, Guillemin, Gilles J.
Publicado no Oncotarget (2015)

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

Por Sundaram, Gayathri, Brew, Bruce J, Jones, Simon P, Adams, Seray, Lim, Chai K, Guillemin, Gilles J
Publicado no J Neuroinflammation (2014)

Role of NAD(+), Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders

Por Essa, Musthafa Mohamed, Subash, Selvaraju, Braidy, Nady, Al-Adawi, Samir, Lim, Chai K, Manivasagam, Tamilarasan, Guillemin, Gilles J
Publicado em 2013

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Por Lim, Chai K., Bilgin, Ayse, Lovejoy, David B., Tan, Vanessa, Bustamante, Sonia, Taylor, Bruce V., Bessede, Alban, Brew, Bruce J., Guillemin, Gilles J.
Publicado no Sci Rep (2017)

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis

Por Lovelace, Michael D., Varney, Bianca, Sundaram, Gayathri, Franco, Nunzio F., Ng, Mei Li, Pai, Saparna, Lim, Chai K., Guillemin, Gilles J., Brew, Bruce J.
Publicado no Front Immunol (2016)

Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

Por Wu, Wei, Nicolazzo, Joseph A., Wen, Li, Chung, Roger, Stankovic, Roger, Bao, Shisan S., Lim, Chai K., Brew, Bruce J., Cullen, Karen M., Guillemin, Gilles J.
Publicado em 2013

Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology

Por Adams, Seray, Teo, Charles, McDonald, Kerrie L., Zinger, Anna, Bustamante, Sonia, Lim, Chai K., Sundaram, Gayathri, Braidy, Nady, Brew, Bruce J., Guillemin, Gilles J.
Publicado no PLoS One (2014)

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

Por Jones, Simon P., Franco, Nunzio F., Varney, Bianca, Sundaram, Gayathri, Brown, David A., de Bie, Josien, Lim, Chai K., Guillemin, Gilles J., Brew, Bruce J.
Publicado no PLoS One (2015)

Connecting inflammation with glutamate agonism in suicidality

Por Erhardt, Sophie, Lim, Chai K, Linderholm, Klas R, Janelidze, Shorena, Lindqvist, Daniel, Samuelsson, Martin, Lundberg, Kristina, Postolache, Teodor T, Träskman-Bendz, Lil, Guillemin, Gilles J, Brundin, Lena
Publicado em 2013

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Por Yan, Edwin B., Frugier, Tony, Lim, Chai K., Heng, Benjamin, Sundaram, Gayathri, Tan, May, Rosenfeld, Jeffrey V., Walker, David W., Guillemin, Gilles J., Morganti-Kossmann, Maria Cristina
Publicado no J Neuroinflammation (2015)

Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages

Por Lim, Chai K., Yap, Margaret M.C., Kent, Stephen J., Gras, Gabriel, Samah, Boubekeur, Batten, Jane C., De Rose, Robert, Heng, Benjamin, Brew, Bruce J., Guillemin, Gilles J.
Publicado em 2013

Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton

Por Dale, Russell C., Tantsis, Esther M., Merheb, Vera, Kumaran, Raani-Yogeeta A., Sinmaz, Nese, Pathmanandavel, Karrnan, Ramanathan, Sudarshini, Booth, David R., Wienholt, Louise A., Prelog, Kristina, Clark, Damien R., Guillemin, Gilles J., Lim, Chai K., Mathey, Emily K., Brilot, Fabienne
Publicado em 2014

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study

Por Chatterjee, Pratishtha, Goozee, Kathryn, Lim, Chai K., James, Ian, Shen, Kaikai, Jacobs, Kelly R., Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, ManYan, Candice, Taddei, Kevin, Lovejoy, David B., Chung, Roger, Guillemin, Gilles J., Martins, Ralph N.
Publicado no Sci Rep (2018)