Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study

The kynurenine pathway (KP) is dysregulated in neuroinflammatory diseases including Alzheimer’s disease (AD), however has not been investigated in preclinical AD characterized by high neocortical amyloid-β load (NAL), prior to cognitive impairment. Serum KP metabolites were measured in the cognitive...

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發表在:Sci Rep
Main Authors: Chatterjee, Pratishtha, Goozee, Kathryn, Lim, Chai K., James, Ian, Shen, Kaikai, Jacobs, Kelly R., Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, ManYan, Candice, Taddei, Kevin, Lovejoy, David B., Chung, Roger, Guillemin, Gilles J., Martins, Ralph N.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964182/
https://ncbi.nlm.nih.gov/pubmed/29789640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25968-7
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