Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease

BACKGROUND: Blood markers indicative of neurodegeneration (neurofilament light chain; NFL), Alzheimer’s disease amyloid pathology (amyloid-β; Aβ), and neuroinflammation (kynurenine pathway; KP metabolites) have been investigated independently in neurodegenerative diseases. However, the association o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroinflammation
Prif Awduron: Chatterjee, Pratishtha, Zetterberg, Henrik, Goozee, Kathryn, Lim, Chai K., Jacobs, Kelly R., Ashton, Nicholas J., Hye, Abdul, Pedrini, Steve, Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, Shen, Kaikai, Taddei, Kevin, Lovejoy, David B., Guillemin, Gilles J., Blennow, Kaj, Martins, Ralph N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788092/
https://ncbi.nlm.nih.gov/pubmed/31601232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1567-4
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