Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease

BACKGROUND: Blood markers indicative of neurodegeneration (neurofilament light chain; NFL), Alzheimer’s disease amyloid pathology (amyloid-β; Aβ), and neuroinflammation (kynurenine pathway; KP metabolites) have been investigated independently in neurodegenerative diseases. However, the association o...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Chatterjee, Pratishtha, Zetterberg, Henrik, Goozee, Kathryn, Lim, Chai K., Jacobs, Kelly R., Ashton, Nicholas J., Hye, Abdul, Pedrini, Steve, Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, Shen, Kaikai, Taddei, Kevin, Lovejoy, David B., Guillemin, Gilles J., Blennow, Kaj, Martins, Ralph N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788092/
https://ncbi.nlm.nih.gov/pubmed/31601232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1567-4
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