Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages

The kynurenine pathway (KP) and one of its end-products, the excitotoxin quinolinic acid (QUIN), are involved in the pathogenesis of several major neuroinflammatory brain diseases. A relevant animal model to study KP metabolism is now needed to assess whether intervention in this pathway may improve...

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Detalhes bibliográficos
Main Authors: Lim, Chai K., Yap, Margaret M.C., Kent, Stephen J., Gras, Gabriel, Samah, Boubekeur, Batten, Jane C., De Rose, Robert, Heng, Benjamin, Brew, Bruce J., Guillemin, Gilles J.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662399/
https://ncbi.nlm.nih.gov/pubmed/23761975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S11789
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