Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton

OBJECTIVE: To examine the clinical features of pediatric CNS demyelination associated with positive myelin oligodendrocyte glycoprotein (MOG) antibodies and to examine the functional effects of MOG antibody on oligodendrocyte cytoskeleton. METHODS: We measured MOG antibody using a fluorescence-activ...

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Detalhes bibliográficos
Main Authors: Dale, Russell C., Tantsis, Esther M., Merheb, Vera, Kumaran, Raani-Yogeeta A., Sinmaz, Nese, Pathmanandavel, Karrnan, Ramanathan, Sudarshini, Booth, David R., Wienholt, Louise A., Prelog, Kristina, Clark, Damien R., Guillemin, Gilles J., Lim, Chai K., Mathey, Emily K., Brilot, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202678/
https://ncbi.nlm.nih.gov/pubmed/25340056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000012
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