Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

The kynurenine pathway is a fundamental mechanism of immunosuppression and peripheral tolerance. It is increasingly recognized as playing a major role in the pathogenesis of a wide variety of inflammatory, neurodegenerative and malignant disorders. However, the temporal dynamics of kynurenine pathwa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jones, Simon P., Franco, Nunzio F., Varney, Bianca, Sundaram, Gayathri, Brown, David A., de Bie, Josien, Lim, Chai K., Guillemin, Gilles J., Brew, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482723/
https://ncbi.nlm.nih.gov/pubmed/26114426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131389
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