Monoclonal antibody higher order structure analysis by high throughput protein conformational array

Por Song, Yuanli, Yu, Deqiang, Mayani, Mukesh, Mussa, Nesredin, Li, Zheng Jian
Publicado no MAbs (2018)

A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation

Por Tang, Peifeng, Xu, Jianlin, Oliveira, Christopher L., Li, Zheng Jian, Liu, Shijie
Publicado no J Enzyme Inhib Med Chem (2017)

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media

Por Xu, Jianlin, Rehmann, Matthew S., Xu, Xuankuo, Huang, Chao, Tian, Jun, Qian, Nan-Xin, Li, Zheng Jian
Publicado no MAbs (2018)

Development of adsorptive hybrid filters to enable two-step purification of biologics

Por Singh, Nripen, Arunkumar, Abhiram, Peck, Michael, Voloshin, Alexei M., Moreno, Angela M., Tan, Zhijun, Hester, Jonathan, Borys, Michael C., Li, Zheng Jian
Publicado no MAbs (2016)

Glycine to glutamic acid misincorporation observed in a recombinant protein expressed by Escherichia coli cells

Por Huang, Yunping, O'Mara, Brian, Conover, Matthew, Ludwig, Richard, Fu, Jinmei, Tao, Li, Li, Zheng Jian, Rieble, Siegfried, Grace, Michael J, Russell, Reb J
Publicado em 2012

Using hydrogen peroxide to prevent antibody disulfide bond reduction during manufacturing process

Por Du, Cheng, Huang, Yunping, Borwankar, Ameya, Tan, Zhijun, Cura, Anthony, Yee, Joon Chong, Singh, Nripen, Ludwig, Richard, Borys, Michael, Ghose, Sanchayita, Mussa, Nesredin, Li, Zheng Jian
Publicado no MAbs (2018)

Understanding and Controlling Sialylation in a CHO Fc-Fusion Process

Por Lewis, Amanda M., Croughan, William D., Aranibar, Nelly, Lee, Alison G., Warrack, Bethanne, Abu-Absi, Nicholas R., Patel, Rutva, Drew, Barry, Borys, Michael C., Reily, Michael D., Li, Zheng Jian
Publicado no PLoS One (2016)

Mechanisms of precipitate formation during the purification of an Fc-fusion protein

Por Greene, Daniel G., Traylor, Steven J., Guo, Jing, Choe, Leila H., Modla, Shannon, Xu, Xuankuo, Singh, Nripen, Lock, Lye Lin, Ghose, Sanchayita, Li, Zheng Jian, Lee, Kelvin H., Wagner, Norman J., Lenhoff, Abraham M.
Publicado no Biotechnol Bioeng (2018)