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Monoclonal antibody higher order structure analysis by high throughput protein conformational array

The elucidation of antibody higher order structure (HOS) is critical in therapeutic antibody development. Since HOS determines the protein bioactivity and chemo-physical properties, this knowledge can help to ensure that the safety and efficacy attributes are not compromised. Protein conformational...

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Pubblicato in:MAbs
Autori principali: Song, Yuanli, Yu, Deqiang, Mayani, Mukesh, Mussa, Nesredin, Li, Zheng Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916549/
https://ncbi.nlm.nih.gov/pubmed/29313446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1421880
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