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Monoclonal antibody higher order structure analysis by high throughput protein conformational array

The elucidation of antibody higher order structure (HOS) is critical in therapeutic antibody development. Since HOS determines the protein bioactivity and chemo-physical properties, this knowledge can help to ensure that the safety and efficacy attributes are not compromised. Protein conformational...

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Podrobná bibliografie
Vydáno v:MAbs
Hlavní autoři: Song, Yuanli, Yu, Deqiang, Mayani, Mukesh, Mussa, Nesredin, Li, Zheng Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916549/
https://ncbi.nlm.nih.gov/pubmed/29313446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1421880
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