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Mechanisms of precipitate formation during the purification of an Fc-fusion protein
Protein precipitates that arise during bioprocessing can cause manufacturing challenges but they can also aid in clearance of host-cell protein and DNA impurities. Such precipitates differ from many protein precipitates that have been studied previously in their heterogeneous composition, particular...
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| Publicado no: | Biotechnol Bioeng |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6185765/ https://ncbi.nlm.nih.gov/pubmed/29896879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26746 |
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