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Purification of monoclonal antibodies by hydrophobic interaction chromatography under no-salt conditions
Hydrophobic interaction chromatography (HIC) is commonly used as a polishing step in monoclonal antibody purification processes. HIC offers an orthogonal selectivity to ion exchange chromatography and can be an effective step for aggregate clearance and host cell protein reduction. HIC, however, suf...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Landes Bioscience
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851231/ https://ncbi.nlm.nih.gov/pubmed/23884181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25552 |
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