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Online Hydrophobic Interaction Chromatography-Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies

Therapeutic monoclonal antibodies (mAbs) are an important class of drugs for a wide spectrum of human diseases. Liquid chromatography (LC) coupled to mass spectrometry (MS) is one of techniques in the forefront for comprehensive characterization of analytical attributes of mAbs. Among various protei...

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Vydáno v:Anal Chem
Hlavní autoři: Chen, Bifan, Lin, Ziqing, Alpert, Andrew J., Fu, Cexiong, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109971/
https://ncbi.nlm.nih.gov/pubmed/29846060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01865
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