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Online Hydrophobic Interaction Chromatography-Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies

Therapeutic monoclonal antibodies (mAbs) are an important class of drugs for a wide spectrum of human diseases. Liquid chromatography (LC) coupled to mass spectrometry (MS) is one of techniques in the forefront for comprehensive characterization of analytical attributes of mAbs. Among various protei...

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Библиографические подробности
Опубликовано в: :Anal Chem
Главные авторы: Chen, Bifan, Lin, Ziqing, Alpert, Andrew J., Fu, Cexiong, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109971/
https://ncbi.nlm.nih.gov/pubmed/29846060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01865
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