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Online Hydrophobic Interaction Chromatography-Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies

Therapeutic monoclonal antibodies (mAbs) are an important class of drugs for a wide spectrum of human diseases. Liquid chromatography (LC) coupled to mass spectrometry (MS) is one of techniques in the forefront for comprehensive characterization of analytical attributes of mAbs. Among various protei...

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Publicado en:Anal Chem
Autores principales: Chen, Bifan, Lin, Ziqing, Alpert, Andrew J., Fu, Cexiong, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109971/
https://ncbi.nlm.nih.gov/pubmed/29846060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01865
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