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Online Hydrophobic Interaction Chromatography-Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies

Therapeutic monoclonal antibodies (mAbs) are an important class of drugs for a wide spectrum of human diseases. Liquid chromatography (LC) coupled to mass spectrometry (MS) is one of techniques in the forefront for comprehensive characterization of analytical attributes of mAbs. Among various protei...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Chen, Bifan, Lin, Ziqing, Alpert, Andrew J., Fu, Cexiong, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109971/
https://ncbi.nlm.nih.gov/pubmed/29846060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01865
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