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Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry

The pharmaceutical industry’s interest in monoclonal antibodies (mAbs) and their derivatives has spurred rapid growth in the commercial and clinical pipeline of these effective therapeutics. The complex micro-heterogeneity of mAbs requires in-depth structural characterization for critical quality at...

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Podrobná bibliografie
Vydáno v:MAbs
Hlavní autoři: Jin, Yutong, Lin, Ziqing, Xu, Qingge, Fu, Cexiong, Zhang, Zhaorui, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343775/
https://ncbi.nlm.nih.gov/pubmed/30230956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1525253
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