Discoidin domain receptor functions in physiological and pathological conditions

af Leitinger, Birgit
Udgivet 2014

Effects of I Domain Deletion on the Function of the β2 Integrin Lymphocyte Function-associated Antigen-1

af Leitinger, Birgit, Hogg, Nancy
Udgivet 2000

Discoidin domain receptors: multitaskers for physiological and pathological processes

af Leitinger, Birgit, Saltel, Frédéric
Udgivet i Cell Adh Migr (2018)

Cell-based Assay for Recruitment of DDR1 to Collagen-coated Beads

af Juskaite, Victoria, Leitinger, Birgit
Udgivet i Bio Protoc (2019)

Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimers

af Juskaite, Victoria, Corcoran, David S, Leitinger, Birgit
Udgivet i eLife (2017)

Two-step release of kinase autoinhibition in discoidin domain receptor 1

af Sammon, Douglas, Hohenester, Erhard, Leitinger, Birgit
Udgivet i Proc Natl Acad Sci U S A (2020)

DISCOIDIN DOMAIN RECEPTOR TYROSINE KINASES: NEW PLAYERS IN CANCER PROGRESSION

af Valiathan, Rajeshwari R., Marco, Marta, Leitinger, Birgit, Kleer, Celina G., Fridman, Rafael
Udgivet 2012

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

af Xu, Huifang, Raynal, Nicolas, Stathopoulos, Stavros, Myllyharju, Johanna, Farndale, Richard W., Leitinger, Birgit
Udgivet 2011

Discoidin Domain Receptors Promote α1β1- and α2β1-Integrin Mediated Cell Adhesion to Collagen by Enhancing Integrin Activation

af Xu, Huifang, Bihan, Dominique, Chang, Francis, Huang, Paul H., Farndale, Richard W., Leitinger, Birgit
Udgivet 2012

Normal Activation of Discoidin Domain Receptor 1 Mutants with Disulfide Cross-links, Insertions, or Deletions in the Extracellular Juxtamembrane Region: MECHANISTIC IMPLICATIONS

af Xu, Huifang, Abe, Takemoto, Liu, Justin K. H., Zalivina, Irina, Hohenester, Erhard, Leitinger, Birgit
Udgivet 2014

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)

af Shitomi, Yasuyuki, Thøgersen, Ida B., Ito, Noriko, Leitinger, Birgit, Enghild, Jan J., Itoh, Yoshifumi
Udgivet i Mol Biol Cell (2015)

A novel form of integrin dysfunction involving β1, β2, and β3 integrins

af McDowall, Alison, Inwald, David, Leitinger, Birgit, Jones, Alison, Liesner, Ri, Klein, Nigel, Hogg, Nancy
Udgivet 2003

Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6

af Hidalgo-Carcedo, Cristina, Hooper, Steven, Chaudhry, Shahid I., Williamson, Peter, Harrington, Kevin, Leitinger, Birgit, Sahai, Erik
Udgivet 2010

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2

af Carafoli, Federico, Bihan, Dominique, Stathopoulos, Stavros, Konitsiotis, Antonios D., Kvansakul, Marc, Farndale, Richard W., Leitinger, Birgit, Hohenester, Erhard
Udgivet 2009

DDR1 autophosphorylation is a result of aggregation into dense clusters

af Corcoran, David S., Juskaite, Victoria, Xu, Yuewei, Görlitz, Frederik, Alexandrov, Yuriy, Dunsby, Christopher, French, Paul M. W., Leitinger, Birgit
Udgivet i Sci Rep (2019)

Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients

af Ali, Bassam R., Xu, Huifang, Akawi, Nadia A., John, Anne, Karuvantevida, Noushad S., Langer, Ruth, Al-Gazali, Lihadh, Leitinger, Birgit
Udgivet 2010

Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

af Carafoli, Federico, Mayer, Marie Cathrin, Shiraishi, Kazushige, Pecheva, Mira Anguelova, Chan, Lai Yi, Nan, Ruodan, Leitinger, Birgit, Hohenester, Erhard
Udgivet 2012

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

af An, Bo, Abbonante, Vittorio, Xu, Huifang, Gavriilidou, Despoina, Yoshizumi, Ayumi, Bihan, Dominique, Farndale, Richard W., Kaplan, David L., Balduini, Alessandra, Leitinger, Birgit, Brodsky, Barbara
Udgivet i J Biol Chem (2016)

Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells

af Rhys, Alexander D., Monteiro, Pedro, Smith, Christopher, Vaghela, Malti, Arnandis, Teresa, Kato, Takuya, Leitinger, Birgit, Sahai, Erik, McAinsh, Andrew, Charras, Guillaume, Godinho, Susana A.
Udgivet i J Cell Biol (2018)

Chain Alignment of Collagen I Deciphered using Computationally Designed Heterotrimers

af Jalan, Abhishek A., Sammon, Douglas, Hartgerink, Jeffrey D., Brear, Paul, Stott, Katherine, Hamaia, Samir W., Hunter, Emma J., Walker, Douglas R., Leitinger, Birgit, Farndale, Richard W.
Udgivet i Nat Chem Biol (2020)