Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

A bacterial collagen-like protein Scl2 has been developed as a recombinant collagen model system to host human collagen ligand-binding sequences, with the goal of generating biomaterials with selective collagen bioactivities. Defined binding sites in human collagen for integrins, fibronectin, hepari...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: An, Bo, Abbonante, Vittorio, Xu, Huifang, Gavriilidou, Despoina, Yoshizumi, Ayumi, Bihan, Dominique, Farndale, Richard W., Kaplan, David L., Balduini, Alessandra, Leitinger, Birgit, Brodsky, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813464/
https://ncbi.nlm.nih.gov/pubmed/26702058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674507
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