Discoidin domain receptor functions in physiological and pathological conditions

nork Leitinger, Birgit
Argitaratua 2014

Effects of I Domain Deletion on the Function of the β2 Integrin Lymphocyte Function-associated Antigen-1

nork Leitinger, Birgit, Hogg, Nancy
Argitaratua 2000

Discoidin domain receptors: multitaskers for physiological and pathological processes

nork Leitinger, Birgit, Saltel, Frédéric
Argitaratua izan da Cell Adh Migr (2018)

Cell-based Assay for Recruitment of DDR1 to Collagen-coated Beads

nork Juskaite, Victoria, Leitinger, Birgit
Argitaratua izan da Bio Protoc (2019)

Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimers

nork Juskaite, Victoria, Corcoran, David S, Leitinger, Birgit
Argitaratua izan da eLife (2017)

Two-step release of kinase autoinhibition in discoidin domain receptor 1

nork Sammon, Douglas, Hohenester, Erhard, Leitinger, Birgit
Argitaratua izan da Proc Natl Acad Sci U S A (2020)

DISCOIDIN DOMAIN RECEPTOR TYROSINE KINASES: NEW PLAYERS IN CANCER PROGRESSION

nork Valiathan, Rajeshwari R., Marco, Marta, Leitinger, Birgit, Kleer, Celina G., Fridman, Rafael
Argitaratua 2012

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

nork Xu, Huifang, Raynal, Nicolas, Stathopoulos, Stavros, Myllyharju, Johanna, Farndale, Richard W., Leitinger, Birgit
Argitaratua 2011

Discoidin Domain Receptors Promote α1β1- and α2β1-Integrin Mediated Cell Adhesion to Collagen by Enhancing Integrin Activation

nork Xu, Huifang, Bihan, Dominique, Chang, Francis, Huang, Paul H., Farndale, Richard W., Leitinger, Birgit
Argitaratua 2012

Normal Activation of Discoidin Domain Receptor 1 Mutants with Disulfide Cross-links, Insertions, or Deletions in the Extracellular Juxtamembrane Region: MECHANISTIC IMPLICATIONS

nork Xu, Huifang, Abe, Takemoto, Liu, Justin K. H., Zalivina, Irina, Hohenester, Erhard, Leitinger, Birgit
Argitaratua 2014

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)

nork Shitomi, Yasuyuki, Thøgersen, Ida B., Ito, Noriko, Leitinger, Birgit, Enghild, Jan J., Itoh, Yoshifumi
Argitaratua izan da Mol Biol Cell (2015)

A novel form of integrin dysfunction involving β1, β2, and β3 integrins

nork McDowall, Alison, Inwald, David, Leitinger, Birgit, Jones, Alison, Liesner, Ri, Klein, Nigel, Hogg, Nancy
Argitaratua 2003

Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6

nork Hidalgo-Carcedo, Cristina, Hooper, Steven, Chaudhry, Shahid I., Williamson, Peter, Harrington, Kevin, Leitinger, Birgit, Sahai, Erik
Argitaratua 2010

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2

nork Carafoli, Federico, Bihan, Dominique, Stathopoulos, Stavros, Konitsiotis, Antonios D., Kvansakul, Marc, Farndale, Richard W., Leitinger, Birgit, Hohenester, Erhard
Argitaratua 2009

DDR1 autophosphorylation is a result of aggregation into dense clusters

nork Corcoran, David S., Juskaite, Victoria, Xu, Yuewei, Görlitz, Frederik, Alexandrov, Yuriy, Dunsby, Christopher, French, Paul M. W., Leitinger, Birgit
Argitaratua izan da Sci Rep (2019)

Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients

nork Ali, Bassam R., Xu, Huifang, Akawi, Nadia A., John, Anne, Karuvantevida, Noushad S., Langer, Ruth, Al-Gazali, Lihadh, Leitinger, Birgit
Argitaratua 2010

Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling

nork Carafoli, Federico, Mayer, Marie Cathrin, Shiraishi, Kazushige, Pecheva, Mira Anguelova, Chan, Lai Yi, Nan, Ruodan, Leitinger, Birgit, Hohenester, Erhard
Argitaratua 2012

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor

nork An, Bo, Abbonante, Vittorio, Xu, Huifang, Gavriilidou, Despoina, Yoshizumi, Ayumi, Bihan, Dominique, Farndale, Richard W., Kaplan, David L., Balduini, Alessandra, Leitinger, Birgit, Brodsky, Barbara
Argitaratua izan da J Biol Chem (2016)

Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells

nork Rhys, Alexander D., Monteiro, Pedro, Smith, Christopher, Vaghela, Malti, Arnandis, Teresa, Kato, Takuya, Leitinger, Birgit, Sahai, Erik, McAinsh, Andrew, Charras, Guillaume, Godinho, Susana A.
Argitaratua izan da J Cell Biol (2018)

Chain Alignment of Collagen I Deciphered using Computationally Designed Heterotrimers

nork Jalan, Abhishek A., Sammon, Douglas, Hartgerink, Jeffrey D., Brear, Paul, Stott, Katherine, Hamaia, Samir W., Hunter, Emma J., Walker, Douglas R., Leitinger, Birgit, Farndale, Richard W.
Argitaratua izan da Nat Chem Biol (2020)