Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control

le Singh, Rajeev, Lauth, Matthias
Foilsithe in J Dev Biol (2017)

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

le Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Foilsithe in Oncotarget (2016)

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

le Lauth, Matthias, Spreafico, Fabio, Dethleffsen, Kathrin, Meyer, Michael
Foilsithe 2002

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

le Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Toftgård, Rune
Foilsithe 2007

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1

le Palaniswamy, Ramesh, Teglund, Stephan, Lauth, Matthias, Zaphiropoulos, Peter G, Shimokawa, Takashi
Foilsithe 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

le Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Foilsithe 2016

Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

le Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Foilsithe 2008

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

le Barski, Jaroslaw J., Denker, Brad M., Guan, Jiazhen, Lauth, Matthias, Spreafico, Fabio, Fertala, Andrzej, Meyer, Michael
Foilsithe 2013

Inhibition of GLI1 gene activation by Patched1

le Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
Foilsithe 2006

Chronic Pancreatitis and Systemic Inflammatory Response Syndrome Prevent Impact of Chemotherapy with Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer()()

le Knoop, Richard F., Sparn, Moritz, Waldmann, Jens, Plassmeier, Lars, Bartsch, Detlef K., Lauth, Matthias, Hudemann, Christoph, Fendrich, Volker
Foilsithe 2014

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

le Fendrich, Volker, Oh, Edwin, Bang, Seungmin, Karikari, Collins, Ottenhof, Niki, Bisht, Savita, Lauth, Matthias, Brossart, Peter, Katsanis, Nicholas, Maitra, Anirban, Feldmann, Georg
Foilsithe 2011

Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

le Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Foilsithe in Cancers (Basel) (2021)

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

le Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Foilsithe in Nat Commun (2015)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

le Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Foilsithe in Nat Commun (2015)

The Immune Microenvironment in Pancreatic Cancer

le Huber, Magdalena, Brehm, Corinna U., Gress, Thomas M., Buchholz, Malte, Alashkar Alhamwe, Bilal, Pogge von Strandmann, Elke, Slater, Emily P., Bartsch, Jörg W., Bauer, Christian, Lauth, Matthias
Foilsithe in Int J Mol Sci (2020)

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

le Joost, Simon, Almada, Luciana L., Rohnalter, Verena, Holz, Philipp S., Vrabel, Anne M., Fernandez-Barrena, Maite G., McWilliams, Robert R., Krause, Michael, Fernandez-Zapico, Martin E., Lauth, Matthias
Foilsithe 2011

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

le Luu, Maik, Pautz, Sabine, Kohl, Vanessa, Singh, Rajeev, Romero, Rossana, Lucas, Sébastien, Hofmann, Jörg, Raifer, Hartmann, Vachharajani, Niyati, Carrascosa, Lucia Campos, Lamp, Boris, Nist, Andrea, Stiewe, Thorsten, Shaul, Yoav, Adhikary, Till, Zaiss, Mario M., Lauth, Matthias, Steinhoff, Ulrich, Visekruna, Alexander
Foilsithe in Nat Commun (2019)

Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancer

le Luu, Maik, Riester, Zeno, Baldrich, Adrian, Reichardt, Nicole, Yuille, Samantha, Busetti, Alessandro, Klein, Matthias, Wempe, Anne, Leister, Hanna, Raifer, Hartmann, Picard, Felix, Muhammad, Khalid, Ohl, Kim, Romero, Rossana, Fischer, Florence, Bauer, Christian A., Huber, Magdalena, Gress, Thomas M., Lauth, Matthias, Danhof, Sophia, Bopp, Tobias, Nerreter, Thomas, Mulder, Imke E., Steinhoff, Ulrich, Hudecek, Michael, Visekruna, Alexander
Foilsithe in Nat Commun (2021)